Introduction Biomarkers can be useful for identifying or ruling out sepsis, identifying patients
who may benefit from specific therapies or assessing the response to therapy. Methods We …

El shock séptico implica la asociación entre infección e insuficiencia hemodinámica, en
algunos casos con fallos viscerales. Las definiciones de shock séptico y sepsis grave …

To study both the pathophysiologic and the prognostic value of ADAMTS13 in thrombotic
microangiopathies (TMAs), we enrolled a cohort of 35 adult patients combining a first acute …

Antibodies with germline or close to germline configuration exist in vertebrates, and these so-
called 'naturally occurring auto-antibodies'(NAb) are directed to self and altered self …

Diaryl esters of α-aminophosphonates are a group of low molecular weight inhibitors of
serine proteases. For over 30 years these molecules have captured the attention of …

Sometime in the mid to late twentieth century the study of antibody‐mediated immunity (AMI)
entered the doldrums, as many immunologists believed that the function of AMI was well …

Although classically B cells are known to play important roles in immune protection via
humoral immunity, recently their regulatory mechanisms have been best appreciated in the …

Autoantibodies against plasma coagulation factors could be developed by some individuals
inducing severe and sometimes fatal bleedings. This clinical entity is called acquired …

The pathologic role of autoantibodies in autoimmune disease is widely accepted. Recently,
we reported that anti-myelin basic protein (MBP) serum Abs from multiple sclerosis (MS) …

Immunoglobulins are known to combine various effector mechanisms of the adaptive and
the innate immune system. Classical immunoglobulin functions are associated with antigen …