Drug-induced liver injury (DILI) is an adverse reaction to drugs or other xenobiotics that
occurs either as a predictable event when an individual is exposed to toxic doses of some …

The gut and the liver are characterized by mutual interactions between both organs, the
microbiome, diet and other environmental factors. The sum of these interactions is …

The role of the gut microbiota in human health is one of the most important research topics.
There is a strong relationship between the microbiota-gut-brain axis and cognitive functions …

Background & Aims Acetaminophen (APAP) induced hepatotoxicity is a leading cause of
acute liver failure worldwide. It is well established that the liver damage induced by …

In current study, larvae and adult zebrafish were exposed to difenoconazole to assess its
effect on hepatotoxicity, lipid metabolism and gut microbiota. Results demonstrated that …

Precise and differential profiling of the dynamic correlations and pathophysiological
implications of multiplex biological mediators with deep penetration and highly programmed …

The gut microbiota not only constitutes intestinal microenvironment homeostasis and human
health but also exerts indispensable roles in the occurrence and progression of multiple liver …

Perfluorooctanoic acid (PFOA), an environmental pollutant, is widely engaged in industrial
products and tends to accumulate in the liver. Emerging evidence has suggested that the gut …

A successful pregnancy depends on not only the tolerance of the fetal immune system by the
mother but also resistance against the threat of hazardous microorganisms. Infection with …

Metabolomics has found numerous applications in the study of liver metabolism in health
and disease. Metabolomics studies can be conducted in a variety of biological matrices …