Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine
Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …
Targeting drug chemo-resistance in cancer using natural products
Cancer is one of the leading causes of death globally. The development of drug resistance
is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms …
is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms …
Natural products for the management and prevention of breast cancer
Among all types of cancer, breast cancer is one of the most challenging diseases, which is
responsible for a large number of cancer related deaths. Hormonal therapy, surgery …
responsible for a large number of cancer related deaths. Hormonal therapy, surgery …
Recent updates on anticancer mechanisms of polyphenols
In today's scenario, when cancer cases are increasing rapidly, anticancer herbal
compounds become imperative. Studies on the molecular mechanisms of action of …
compounds become imperative. Studies on the molecular mechanisms of action of …
Role of silymarin in cancer treatment: facts, hypotheses, and questions
The flavonoid silymarin extracted from the seeds of Sylibum marianum is a mixture of 6
flavolignan isomers. The 3 more important isomers are silybin (or silibinin), silydianin, and …
flavolignan isomers. The 3 more important isomers are silybin (or silibinin), silydianin, and …
Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance
In the last few decades, targeting cancer by the use of dietary phytochemicals has gained
enormous attention. The plausible reason and believe or mind set behind this fact is …
enormous attention. The plausible reason and believe or mind set behind this fact is …
The anti-cancer effect of polyphenols against breast cancer and cancer stem cells: molecular mechanisms
The high incidence of breast cancer in developed and developing countries, and its
correlation to cancer-related deaths, has prompted concerned scientists to discover novel …
correlation to cancer-related deaths, has prompted concerned scientists to discover novel …
Autophagy: Mechanisms and therapeutic potential of flavonoids in cancer
X Pang, X Zhang, Y Jiang, Q Su, Q Li, Z Li - Biomolecules, 2021 - mdpi.com
Autophagy, which is a conserved biological process and essential mechanism in
maintaining homeostasis and metabolic balance, enables cells to degrade cytoplasmic …
maintaining homeostasis and metabolic balance, enables cells to degrade cytoplasmic …
Silibinin inhibits migration and invasion of breast cancer MDA-MB-231 cells through induction of mitochondrial fusion
L Si, J Fu, W Liu, T Hayashi, Y Nie, K Mizuno… - Molecular and cellular …, 2020 - Springer
Human triple negative breast cancer cells, MDA-MB-231, show typical epithelial to
mesenchymal transition associated with cancer progression. Mitochondria play a major role …
mesenchymal transition associated with cancer progression. Mitochondria play a major role …
Targeting cancer with phytochemicals via their fine tuning of the cell survival signaling pathways
The role of phytochemicals as potential prodrugs or therapeutic substances against tumors
has come in the spotlight in the very recent years, thanks to the huge mass of encouraging …
has come in the spotlight in the very recent years, thanks to the huge mass of encouraging …