Germline rare variants in HER2-positive breast cancer predisposition: a systematic review and meta-analysis

AC de Baumont, NA Cadore, LG Pedrotti… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Introduction Approximately 10% of breast cancer (BC) cases result from hereditary causes.
Genetic testing has been widely implemented in BC care to determine hereditary cancer …

Spectrum of germline pathogenic variants in Brazilian hereditary breast/ovarian cancer cases

JP Faria, JG Assumpção, L de Oliveira Matos… - Breast Cancer Research …, 2024 - Springer
Purpose To define the spectrum of germline pathogenic variants (PVs) and copy number
variant (CNV) in cancer susceptibility genes to the burden of breast and ovarian cancer (BC …

Germline mutations of breast cancer susceptibility genes through expanded genetic analysis in unselected Colombian patients

DC Sierra-Díaz, A Morel, DJ Fonseca-Mendoza… - Human Genomics, 2024 - Springer
Abstract Background In Colombia and worldwide, breast cancer (BC) is the most frequently
diagnosed neoplasia and the leading cause of death from cancer among women. Studies …

[HTML][HTML] A portrait of germline pathogenic variants in high and moderate penetrance breast cancer genes in Brazil

LJ de Carvalho Oliveira, AM Rodrigues… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Introduction The prevalence of germline pathogenic/likely pathogenic variants (P/LP) in high
and moderate penetrance (HMP) genes is approximately 7%–10% among breast cancer …

Asociación de los factores de riesgo modificables y los factores genéticos con el fenotipo tumoral y desenlaces clínicos de pacientes colombianas con síndrome de …

AL Montealegre Páez - repositorio.unal.edu.co
Introducción: El cáncer de mama y el cáncer de ovario son unos de los cánceres más
prevalentes tanto a nivel mundial como en nuestro país, entre el 5 y el 10% de estos …