Brain–body communication in metabolic control

A Furlan, P Petrus - Trends in Endocrinology & Metabolism, 2023 - cell.com
A thorough understanding of the mechanisms controlling energy homeostasis is needed to
prevent and treat metabolic morbidities. While the contribution of organs such as the liver …

[HTML][HTML] Hungry for relief: Potential for neurotensin to address comorbid obesity and pain

R Khan, G Laumet, GM Leinninger - Appetite, 2024 - Elsevier
Chronic pain and obesity frequently occur together. An ideal therapy would alleviate pain
without weight gain, and most optimally, could promote weight loss. The neuropeptide …

[HTML][HTML] Obesity: a prerequisite for major chronic illnesses

HA Afolabi, Z Zakaria, SM Salleh… - … -Recent Insights and …, 2023 - intechopen.com
Obesity is rampantly soaring at an alarming rate globally and simultaneously causing an
increased incidence, and predisposition to various comorbidities. obesity is body mass …

Current perspectives on brain circuits involved in food addiction-like behaviors

E Senol, H Mohammad - Journal of Neural Transmission, 2024 - Springer
There is an emerging view that the increased availability of energy-dense foods in our
society is contributing to excessive food consumption which could lead to food addiction-like …

Neurotensin receptor‐1 antagonist SR48692 modulation of high‐fat diet–induced pathogenesis of NAFLD in mice

H Pal, P Verma, B Mohanty - European Journal of Lipid …, 2024 - Wiley Online Library
This study investigates the efficacy of the antagonist of neurotensin receptor‐1 (NTSR1)
SR48692 in modulating the high‐fat diet (HFD)‐induced nonalcoholic fatty liver disease …

Food and water uptake are regulated by distinct central amygdala circuits revealed using intersectional genetics

F Fermani, S Chang, C Peters, L Gaitanos… - bioRxiv, 2024 - biorxiv.org
The central amygdala (CeA) plays a crucial role in defensive and appetitive behaviours. It
contains genetically defined GABAergic neuron subpopulations distributed over three …

A molecularly distinct accumbal-to-lateral hypothalamic circuit modulates food seeking and consumption

Y Liu, Z Zhao, G Xie, R Chen, Y Zhang - bioRxiv, 2023 - biorxiv.org
Understanding the mechanism of energy homeostasis is expected to lead to effective
treatment to obesity and metabolic diseases,. However, energy homeostasis is a …

Autorregulação do córtex pré-frontal e sua relação com a tolerância ao exercício físico e com o acúmulo de gordura corporal

WQA Silva - 2023 - repositorio.ufrn.br
RESUMO A inatividade física é considerada um dos maiores problemas de saúde pública
global, e compreender mecanismos associados de forma integrada é fundamental para …

[PDF][PDF] The Central Amygdala Encodes Nutritional Properties and Modulates Weight Gain

S Boyle - 2023 - repository.cshl.edu
Foods high in fat and sugar are increasing in prevalence, with many middle-or highincome
countries blowing past the recommended nutritional levels90, 91. In parallel, metabolic …

Room for dessert? How neurons in the amygdala encode for overeating of palatable foods.

K Fabien - Ottawa-Carleton Journal of Neuroethology, 2024 - ojs.scholarsportal.info
The prevalence of obesity is rapidly increasing, mainly being caused by poor dietary
choices, lack of physical activity, and overeating. Apart from some rare genetic conditions …