Protein phosphorylation is one of the most widely observed and important post-translational
modification (PTM) processes. Protein phosphorylation is regulated by protein kinases, each …

The central dogma of modern biology underscores the pivotal roles proteins play in diverse
biological processes, the study of which necessitates advanced methods to produce …

CK2 denotes a ubiquitous and pleiotropic protein kinase whose holoenzyme is composed of
two catalytic (α and/or α′) and two regulatory β subunits. The CK2 consensus sequence …

Spermatogenesis is a complex cell differentiation process that includes marked genetic,
cellular, functional and structural changes. It requires tight regulation, because disturbances …

Protein phosphorylation at distinct tyrosine residues (pY) is essential for fast, specific, and
accurate signal transduction in cells. Enrichment of pY-containing peptides derived from …

Protein phosphorylation is a critical way that cells respond to external signals and
environmental stresses. However, the patterns of cellular response to chemicals at different …

Ecto‑protein kinases, including protein kinase CK2 (former name, casein kinase 2), have
been the focus of research for more than 30 years. At the beginning of the ecto‑kinase …

Molecular imprinting, known as a superior technique for making artificial antibodies, always
suffers from template optimization in terms of distribution and orientation for specific …

The complex and heterogeneous pathophysiology of schizophrenia can be deconstructed
by integration of large-scale datasets encompassing genes through behavioral phenotypes …

Kinomics is an emerging field of science that involves the study of global kinase activity. As
kinases are essential players in virtually all cellular activities, kinomic testing can directly …