MicroRNA as an important target for anticancer drug development
Z Fu, L Wang, S Li, F Chen, KKW Au-Yeung… - Frontiers in …, 2021 - frontiersin.org
Cancer has become the second greatest cause of death worldwide. Although there are
several different classes of anticancer drugs that are available in clinic, some tough issues …
several different classes of anticancer drugs that are available in clinic, some tough issues …
Targeting rac and Cdc42 GTPases in cancer
MM Maldonado, S Dharmawardhane - Cancer research, 2018 - AACR
Rac and Cdc42 are small GTPases that have been linked to multiple human cancers and
are implicated in epithelial to mesenchymal transition, cell-cycle progression …
are implicated in epithelial to mesenchymal transition, cell-cycle progression …
Circular RNAs (circRNAs) in cancer
Circular RNAs (circRNAs) are a class of non-coding RNAs that do not have 5′ end caps or
3′ end poly (A) tails. There are more than one hundred thousand genes that encode …
3′ end poly (A) tails. There are more than one hundred thousand genes that encode …
Emerging microRNA biomarkers for colorectal cancer diagnosis and prognosis
B Chen, Z Xia, YN Deng, Y Yang… - Royal Society …, 2019 - royalsocietypublishing.org
MicroRNAs (miRNAs) are one abundant class of small, endogenous non-coding RNAs,
which regulate various biological processes by inhibiting expression of target genes …
which regulate various biological processes by inhibiting expression of target genes …
MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications
AM Strubberg, BB Madison - Disease models & …, 2017 - journals.biologists.com
MicroRNAs (miRNAs) are small single-stranded RNAs that repress mRNA translation and
trigger mRNA degradation. Of the∼ 1900 miRNA-encoding genes present in the human …
trigger mRNA degradation. Of the∼ 1900 miRNA-encoding genes present in the human …
[HTML][HTML] Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Νew trends in the development of miRNA therapeutic strategies in oncology
R Gambari, E Brognara… - … journal of oncology, 2016 - spandidos-publications.com
MicroRNA (miRNA or miR) therapeutics in cancer are based on targeting or mimicking
miRNAs involved in cancer onset, progression, angiogenesis, epithelial-mesenchymal …
miRNAs involved in cancer onset, progression, angiogenesis, epithelial-mesenchymal …
Good or not good: Role of miR-18a in cancer biology
T Kolenda, K Guglas, M Kopczyńska… - Reports of Practical …, 2020 - journals.viamedica.pl
Abstract miR-18a is a member of primary transcript called miR-17-92a (C13orf25 or
MIR17HG) which also contains five other miRNAs: miR-17, miR-19a, miR-20a, miR-19b and …
MIR17HG) which also contains five other miRNAs: miR-17, miR-19a, miR-20a, miR-19b and …
Biomarkers in cancer detection, diagnosis, and prognosis
Biomarkers are vital in healthcare as they provide valuable insights into disease diagnosis,
prognosis, treatment response, and personalized medicine. They serve as objective …
prognosis, treatment response, and personalized medicine. They serve as objective …
The PI3K/Akt/mTOR axis in colorectal cancer: oncogenic alterations, non‐coding RNAs, therapeutic opportunities, and the emerging role of nanoparticles
MJ Sanaei… - Journal of Cellular …, 2022 - Wiley Online Library
Colorectal cancer (CRC) is one of the deadliest human malignancies worldwide. Several
molecular pathways have been demonstrated to be involved in the initiation and …
molecular pathways have been demonstrated to be involved in the initiation and …
Long non-coding RNA UCA1 enhances tamoxifen resistance in breast cancer cells through a miR-18a-HIF1α feedback regulatory loop
X Li, Y Wu, A Liu, X Tang - Tumor Biology, 2016 - Springer
Recent studies reported that long non-coding RNAs (lncRNAs) might play critical roles in
regulating endocrine resistance of breast cancer. Urothelial carcinoma-associated 1 (UCA1) …
regulating endocrine resistance of breast cancer. Urothelial carcinoma-associated 1 (UCA1) …