The canonical histone proteins are encoded by replication-dependent genes and must
rapidly reach high levels of expression during S phase. In metazoans the genes that encode …

Plant speciation and diversification strongly rely on structural changes in the nuclear
genome, both at the whole ploidy and individual chromosome level. Phylogenetic …

Production of haploid plants that inherit chromosomes from only one parent can greatly
accelerate plant breeding,,. Haploids generated from a heterozygous individual and …

The histone H3 variant CenH3, called CENP-A in humans, is central in centromeric
chromatin to ensure proper chromosome segregation. In the absence of an underlying DNA …

The assembly of just a single kinetochore at the centromere of each sister chromatid is
essential for accurate chromosome segregation during cell division. Surprisingly, despite …

A major challenge in nuclear organization is the packaging of DNA into dynamic chromatin
structures that can respond to changes in the transcriptional requirements of the cell …

Satellite DNAs (tandemly repeated, non-coding DNA sequences) stretch over almost all
native centromeres and surrounding pericentromeric heterochromatin. Once considered as …

Satellite DNAs represent the most abundant fraction of repetitive sequences in genomes of
almost all eukaryotic species. Long arrays of satellite DNA monomers form densely packed …

Fidelity during chromosome segregation is essential to prevent aneuploidy. The proteins
and chromatin at the centromere form a unique site for kinetochore attachment and allow the …

Chromosome segregation ensures that DNA is equally divided between daughter cells
during each round of cell division. The centromere (CEN) is the specific locus on each …