The diversity of histone versus nonhistone sirtuin substrates
P Martínez-Redondo, A Vaquero - Genes & cancer, 2013 - journals.sagepub.com
The members of the Sir2 family, or sirtuins, are major regulators of the response to different
types of stress. The members of the family have adapted to increasing complexities …
types of stress. The members of the family have adapted to increasing complexities …
Translational regulation in blood stages of the malaria parasite Plasmodium spp.: systems‐wide studies pave the way
The malaria parasite Plasmodium spp. varies the expression profile of its genes depending
on the host it resides in and its developmental stage. Virtually all messenger RNA (mRNA) is …
on the host it resides in and its developmental stage. Virtually all messenger RNA (mRNA) is …
Genome-wide real-time in vivo transcriptional dynamics during Plasmodium falciparum blood-stage development
Genome-wide analysis of transcription in the malaria parasite Plasmodium falciparum has
revealed robust variation in steady-state mRNA abundance throughout the 48-h …
revealed robust variation in steady-state mRNA abundance throughout the 48-h …
Exploring the virulence gene interactome with CRISPR/dC as9 in the human malaria parasite
Mutually exclusive expression of the var multigene family is key to immune evasion and
pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct …
pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct …
Proteome-Wide Identification of RNA-dependent proteins and an emerging role for RNAs in Plasmodium falciparum protein complexes
Ribonucleoprotein complexes are composed of RNA, RNA-dependent proteins (RDPs) and
RNA-binding proteins (RBPs), and play fundamental roles in RNA regulation. However, in …
RNA-binding proteins (RBPs), and play fundamental roles in RNA regulation. However, in …
Novel anti-inflammatory activity of epoxyazadiradione against macrophage migration inhibitory factor: inhibition of tautomerase and proinflammatory activities of …
Macrophage migration inhibitory factor (MIF) is responsible for proinflammatory reactions in
various infectious and non-infectious diseases. We have investigated the mechanism of anti …
various infectious and non-infectious diseases. We have investigated the mechanism of anti …
A bioinformatic survey of RNA-binding proteins in Plasmodium
Background The malaria parasites in the genus Plasmodium have a very complicated life
cycle involving an invertebrate vector and a vertebrate host. RNA-binding proteins (RBPs) …
cycle involving an invertebrate vector and a vertebrate host. RNA-binding proteins (RBPs) …
The PfAlba1 RNA-binding protein is an important regulator of translational timing in Plasmodium falciparum blood stages
SS Vembar, CR Macpherson, O Sismeiro, JY Coppée… - Genome biology, 2015 - Springer
Background Transcriptome-wide ribosome occupancy studies have suggested that during
the intra-erythrocytic lifecycle of Plasmodium falciparum, select mRNAs are post …
the intra-erythrocytic lifecycle of Plasmodium falciparum, select mRNAs are post …
Transcriptomic analysis reveals reduced transcriptional activity in the malaria parasite Plasmodium cynomolgi during progression into dormancy
NL Bertschi, A Voorberg-Van der Wel, AM Zeeman… - Elife, 2018 - elifesciences.org
Relapses of Plasmodium dormant liver hypnozoites compromise malaria eradication efforts.
New radical cure drugs are urgently needed, yet the vast gap in knowledge of hypnozoite …
New radical cure drugs are urgently needed, yet the vast gap in knowledge of hypnozoite …
The Alba protein family: Structure and function
Alba family proteins are small, basic, dimeric nucleic acid-binding proteins, which are widely
distributed in archaea and a number of eukaryotes. This family of proteins bears the distinct …
distributed in archaea and a number of eukaryotes. This family of proteins bears the distinct …