Over the past several years neurobiologists have engaged in intense study of
neurotransmitter receptor-gated ion cham~ ls. Their presence in neuronal and eon-neuro …

The purpose of this review is to present current views on the molecular structure of the
GABAA receptor, as derived from biochemical investigations. Included also will be an …

The gamma-aminobutyric acid/benzodiazepine receptor from bovine cerebral cortex was
solubilized with sodium deoxycholate and purified by affinity chromatography on …

A gamma-aminobutyrate/benzodiazepine receptor complex has been purified from bovine
cerebral cortex by an improved procedure using a zwitterionic detergent. A high affinity …

Agonists of benzodiazepine (BZD) binding site in GABA receptors are widely used in clinical
practice. In spite of their benefits they have several side effects, so synthesis of new agonists …

Benzodiazepines are among the most widely used drugs. In 1973, approximately 15% of the
adult population in the West admitted to having used benzodiazepines (BZ) at least once …

Biochemical dissection of the gamma-aminobutyrate synapse. - PMC Back to Top Skip to
main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …

3-Substituted 6-phenyl-4 H-imidazo [1, 5-a][1, 4] benzodiazepines and related compounds
were synthesized as central benzodiazepine receptor (CBR) ligands. Most of the …

The benzodiazepines were introduced into clinical practice in 1960 and since that time have
become one of the most frequently prescribed of all psychotropic agents. Over the past 25 …

This paper reports the synthesis and binding assays toward benzodiazepine and adenosine
A1 and A2A receptors of new 1, 2, 3-triazolo [1, 5-a] quinoxalin-4-one derivatives. The …