New therapeutics such as antisense oligonucleotides, small interfering RNA and peptide-
drug conjugates are taking great relevance in the pharmaceutical industry due to their …

Abstract The Biopharmaceutics Classification System (BCS) classifies pharmaceutical
compounds based on their aqueous solubility and intestinal permeability. The BCS Class III …

The high rise in the population suffering from depression depicts the need for improved and
highly effective treatment options for this condition. Efforts to develop existing drugs into user …

Purpose The aim of current study was to use methylene blue-curcumin ion pair
nanoparticles and single dyes as photosensitizer for comparison of photodynamic therapy …

The interaction of methylene blue (MB) as a photosensitizer with graphene oxide nano-
sheets (GO) was examined in aqueous solution using UV-vis spectrophotometric …

To ensure the optimal performance of oral controlled release formulations, drug colon
permeability is one of the critical parameters. Consequently developing this kind of …

This study shows the effect of ion pair formation on intestinal absorption and oral
bioavailability of amifostine. Amifostine is a prodrug used as a highly potent and selective …

Curcumin and salicylic acid are both phenolic compounds and they can both affect cancer
treatment efficacy. In this study, the effects of methylene blue-curcumin (CU-MB) and …

Acyclovir is a BCS class III drug that has high solubility and low permeability. Acyclovir is an
antiviral drug used for the treatment of herpes simplex and varicose zoster. d-glucose is …

This study presents the results of in vitro evaluation of a series of organic counter ions that
form ion pairs with amifostine. The selected counter ions have different lipophilicity, shape …