Fibroblasts as turned agents in cancer progression
R Wieder - Cancers, 2023 - mdpi.com
Simple Summary Normal epithelial cells in our organs are surrounded by stroma, which is
an ecosystem made up of a variety of cells and proteins that support their intended functions …
an ecosystem made up of a variety of cells and proteins that support their intended functions …
Theranostics in targeting fibroblast activation protein bearing cells: progress and challenges
Cancer cells are surrounded by a complex and highly dynamic tumor microenvironment
(TME). Cancer-associated fibroblasts (CAFs), a critical component of TME, contribute to …
(TME). Cancer-associated fibroblasts (CAFs), a critical component of TME, contribute to …
Clinical evaluation of 68Ga-FAPI-RGD for imaging of fibroblast activation protein and integrin αvβ3 in various cancer types
L Zhao, X Wen, W Xu, Y Pang, L Sun… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Radiolabeled fibroblast activation protein (FAP) inhibitors (FAPIs) and Arg-Gly-Asp (RGD)
peptides have been extensively investigated for imaging of FAP-and integrin αvβ3–positive …
peptides have been extensively investigated for imaging of FAP-and integrin αvβ3–positive …
Synthesis and Preclinical Evaluation of Three Novel 68Ga-Labeled Bispecific PSMA/FAP-Targeting Tracers for Prostate Cancer Imaging
A Verena, Z Zhang, HT Kuo, H Merkens, J Zeisler… - Molecules, 2023 - mdpi.com
Tumor heterogeneity limits the efficacy and reliability of monospecific radiopharmaceuticals
in prostate cancer diagnosis and therapy. To overcome this limitation and improve lesion …
in prostate cancer diagnosis and therapy. To overcome this limitation and improve lesion …
Lu-177-Labeled Hetero-Bivalent Agents Targeting PSMA and Bone Metastases for Radionuclide Therapy
Z Zha, K Ploessl, SR Choi, R Zhao, W Jin… - Journal of Medicinal …, 2023 - ACS Publications
Prostate-specific membrane antigen (PSMA) is an excellent target for imaging and
radionuclide therapy of prostate cancer. Recently,[177Lu] Lu-PSMA-617 (Pluvicto) was …
radionuclide therapy of prostate cancer. Recently,[177Lu] Lu-PSMA-617 (Pluvicto) was …
Preclinical evaluation of a fibroblast activation protein and a prostate-specific membrane antigen dual-targeted probe for noninvasive prostate cancer imaging
P Wang, S Wang, F Liu, Y Ren, Q Guo… - Molecular …, 2023 - ACS Publications
Prostate-specific membrane antigen (PSMA) is a prostate cancer target that plays a crucial
role in prostate cancer diagnosis and therapy. Herein, a novel dual-targeted imaging …
role in prostate cancer diagnosis and therapy. Herein, a novel dual-targeted imaging …
Recent pre-clinical advancements in nuclear medicine: pioneering the path to a limitless future
W Echavidre, D Fagret, M Faraggi, V Picco… - Cancers, 2023 - mdpi.com
Simple Summary This review summarizes recent advances in the nuclear medicine
theranostic approach. It covers the repurposing of historical radiotracers for new indications …
theranostic approach. It covers the repurposing of historical radiotracers for new indications …
Carrier systems of radiopharmaceuticals and the application in cancer therapy
T Zhang, H Lei, X Chen, Z Dou, B Yu, W Su… - Cell Death …, 2024 - nature.com
Radiopharmaceuticals play a vital role in cancer therapy. The carrier of
radiopharmaceuticals can precisely locate and guide radionuclides to the target, where …
radiopharmaceuticals can precisely locate and guide radionuclides to the target, where …
Synthesis and preclinical evaluation of a heterodimeric radioligand targeting fibroblast activation protein and integrin-αvβ3
Q Yan, J Zhong, Y Liu, S Peng, P Feng, Y Zhong… - European Journal of …, 2023 - Elsevier
Tumor progression is accompanied by intrinsic heterogeneity and different phenotypes,
which implies a different expression of cell surface receptors. Fibroblast activation protein …
which implies a different expression of cell surface receptors. Fibroblast activation protein …
[HTML][HTML] The application of radiolabeled targeted molecular probes for the diagnosis and treatment of prostate cancer
L Cheng, T Yang, J Zhang, F Gao… - Korean Journal of …, 2023 - ncbi.nlm.nih.gov
Radiopharmaceuticals targeting prostate-specific membrane antigens (PSMA) are essential
for the diagnosis, evaluation, and treatment of prostate cancer (PCa), particularly metastatic …
for the diagnosis, evaluation, and treatment of prostate cancer (PCa), particularly metastatic …