Challenges in clinical development of mesenchymal stromal/stem cells: concise review

I Mastrolia, EM Foppiani, A Murgia… - Stem cells …, 2019 - academic.oup.com
Identified 50 years ago, mesenchymal stromal/stem cells (MSCs) immediately generated a
substantial interest among the scientific community because of their differentiation plasticity …

Adipose tissue-derived stem cells: immunomodulatory effects and therapeutic potential

S Al-Ghadban, BA Bunnell - Physiology, 2020 - journals.physiology.org
Adipose-derived stem cells (ASCs) can self-renew and differentiate along multiple cell
lineages. ASCs are also potently anti-inflammatory due to their inherent ability to regulate …

Exosomes from adipose-derived stem cells promote chondrogenesis and suppress inflammation by upregulating miR-145 and miR-221

C Zhao, JY Chen, WM Peng… - Molecular …, 2020 - spandidos-publications.com
Osteoarthritis (OA) is one of the most prevalent joint disorders globally. Patients suffering
from OA are often obese and adiposity is linked to chronic inflammation. In the present study …

Adipose tissue stem cells for therapy: an update on the progress of isolation, culture, storage, and clinical application

DT Chu, T Nguyen Thi Phuong, NLB Tien… - Journal of Clinical …, 2019 - mdpi.com
Adipose tissue stem cells (ASCs), known as multipotent stem cells, are most commonly used
in the clinical applications in recent years. Adipose tissues (AT) have the advantage in the …

Stromal vascular fraction promotes migration of fibroblasts and angiogenesis through regulation of extracellular matrix in the skin wound healing process

H Bi, H Li, C Zhang, Y Mao, F Nie, Y Xing… - Stem cell research & …, 2019 - Springer
Background A refractory wound is a typical complication of diabetes and is a common
outcome after surgery. Current approaches have difficulty in improving wound healing …

Challenges and translational considerations of mesenchymal stem/stromal cell therapy for Parkinson's disease

D Fričová, JA Korchak, AC Zubair - NPJ Regenerative medicine, 2020 - nature.com
Parkinson's disease (PD) is the second most common neurodegenerative disease
characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars …

Adipose-derived mesenchymal stromal cells in basic research and clinical applications

K Czerwiec, M Zawrzykraj, M Deptuła… - International Journal of …, 2023 - mdpi.com
Adipose-derived mesenchymal stromal cells (AD-MSCs) have been extensively studied in
recent years. Their attractiveness is due to the ease of obtaining clinical material (fat tissue …

[HTML][HTML] Translational products of adipose tissue-derived mesenchymal stem cells: Bench to bedside applications

S Sharma, S Muthu, M Jeyaraman… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
With developments in the field of tissue engineering and regenerative medicine, the use of
biological products for the treatment of various disorders has come into the limelight among …

Mesenchymal stem/progenitor cells: the prospect of human clinical translation

D Rady, MMS Abbass, AA El-Rashidy… - Stem Cells …, 2020 - Wiley Online Library
Mesenchymal stem/progenitor cells (MSCs) are key players in regenerative medicine,
relying principally on their differentiation/regeneration potential, immunomodulatory …

A role for adipocytes and adipose stem cells in the breast tumor microenvironment and regenerative medicine

CK Brock, KL Hebert, M Artiles, MK Wright… - Frontiers in …, 2021 - frontiersin.org
Obesity rates are climbing, representing a confounding and contributing factor to many
disease states, including cancer. With respect to breast cancer, obesity plays a prominent …