Isoprostanes (IsoPs) are prostaglandin-like molecules generated independent of the
cyclooxygenase (COX) by the free radical-induced peroxidation of arachidonic acid. The first …

抄録 There has been much evidence demonstrating the involvement of oxidative stress in
the pathology of neurological disorders. Moreover, the vulnerability of the central nervous …

Lying at the intersection between neurobiology and epigenetics, Rett syndrome (RTT) has
garnered intense interest in recent years, not only from a broad range of academic scientists …

ASDs (autism spectrum disorders) are a complex group of neurodevelopment disorders, still
poorly understood, steadily rising in frequency and treatment refractory. Extensive research …

Polyunsaturated fatty acids (PUFAs) are essential components in eukaryotic cell membrane.
They take part in the regulation of cell signalling pathways and act as precursors in …

Rett syndrome (RTT) is a rare neurodevelopmental disorder affecting almost exclusively
females, caused in the overwhelming majority of the cases by loss-of-function mutations in …

Metabolites of non-enzymatic lipid peroxidation of polyunsaturated fatty acids notably
omega-3 and omega-6 fatty acids have become important biomarkers of lipid products …

The main cause of Rett syndrome (RTT), a pervasive development disorder almost
exclusively affecting females, is a mutation in the methyl‐CpG binding protein 2 (MeCP2) …

An involvement of the immune system has been suggested in Rett syndrome (RTT), a
devastating neurodevelopmental disorder related to oxidative stress, and caused by a …

Cyclic oxygenated metabolites are formed in vivo through non-enzymatic free radical
reaction of n-6 and n-3 polyunsaturated fatty acids (PUFAs) such as arachidonic (ARA C20 …