A key facet of alcohol use disorder is continuing to drink alcohol despite negative
consequences (so called “aversion-resistant drinking”). In this study, we sought to assess …

Background Biological factors are known to influence disease trajectories and treatment
effectiveness in alcohol addiction and preclinical and clinical evidence suggests that sex is …

Abstract Alcohol Use Disorder (AUD) adversely affects the lives of millions of people, but still
lacks effective treatment options. Recent advancements in psychedelic research suggest …

Recently we identified a deficiency in metabotropic glutamate receptor 2 (mGlu2) function in
the corticoaccumbal pathway, as a common pathological mechanism underlying alcohol …

Despite impressive results from neuroscience research using rodent models, there is a
paucity of successful translation from preclinical findings to effective pharmacological …