Non-consummatory behavior signals predict aversion-resistant alcohol drinking in head-fixed mice
NM Timme, CE Ardinger, SDC Weir… - …, 2024 - Elsevier
A key facet of alcohol use disorder is continuing to drink alcohol despite negative
consequences (so called “aversion-resistant drinking”). In this study, we sought to assess …
consequences (so called “aversion-resistant drinking”). In this study, we sought to assess …
Sex-and age-specific effects on the development of addiction and compulsive-like drinking in rats
Background Biological factors are known to influence disease trajectories and treatment
effectiveness in alcohol addiction and preclinical and clinical evidence suggests that sex is …
effectiveness in alcohol addiction and preclinical and clinical evidence suggests that sex is …
Psilocybin-induced default mode network hypoconnectivity is blunted in alcohol-dependent rats
JR Reinwald, CN Schmitz, I Skorodumov… - Translational …, 2023 - nature.com
Abstract Alcohol Use Disorder (AUD) adversely affects the lives of millions of people, but still
lacks effective treatment options. Recent advancements in psychedelic research suggest …
lacks effective treatment options. Recent advancements in psychedelic research suggest …
[HTML][HTML] mGlu2 mechanism-based interventions to treat alcohol relapse
V Vengeliene, R Spanagel - Frontiers in pharmacology, 2022 - frontiersin.org
Recently we identified a deficiency in metabotropic glutamate receptor 2 (mGlu2) function in
the corticoaccumbal pathway, as a common pathological mechanism underlying alcohol …
the corticoaccumbal pathway, as a common pathological mechanism underlying alcohol …
[HTML][HTML] Socially Integrated Polysubstance (SIP) system: An open-source solution for continuous monitoring of polysubstance fluid intake in group housed mice
Despite impressive results from neuroscience research using rodent models, there is a
paucity of successful translation from preclinical findings to effective pharmacological …
paucity of successful translation from preclinical findings to effective pharmacological …