The rat animal model for noise-induced hearing loss

CD Escabi, MD Frye, M Trevino… - The Journal of the …, 2019 - pubs.aip.org
Rats make excellent models for the study of medical, biological, genetic, and behavioral
phenomena given their adaptability, robustness, survivability, and intelligence. The rat's …

Tailoring of novel azithromycin-loaded zinc oxide nanoparticles for wound healing

MS Saddik, MMA Elsayed, MA El-Mokhtar, H Sedky… - Pharmaceutics, 2022 - mdpi.com
Skin is the largest mechanical barrier against invading pathogens. Following skin injury, the
healing process immediately starts to regenerate the damaged tissues and to avoid …

Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis

DF Colón, CW Wanderley, M Franchin, CM Silva… - Critical Care, 2019 - Springer
Abstract Background Neutrophil extracellular traps (NETs) are innate defense mechanisms
that are also implicated in the pathogenesis of organ dysfunction. However, the role of NETs …

Immunomodulatory and anti-inflammatory effects of hydro-ethanolic extract of Ocimum basilicum leaves and its effect on lung pathological changes in an ovalbumin …

N Eftekhar, A Moghimi… - … and alternative medicine, 2019 - Springer
Abstract Background Ocimum species (Lamiaceae) has been traditionally used for treatment
of upper respiratory tract infections, bronchitis, coughs, sore throat, and wound healing. The …

Integrated metabolomics and proteomics analysis of hippocampus in a rat model of depression

Y Zhang, S Yuan, J Pu, L Yang, X Zhou, L Liu, X Jiang… - Neuroscience, 2018 - Elsevier
Major depressive disorder (MDD) is a prevalent and serious mental disorder with high rates
of suicide and disability. However, the underlying pathogenesis of MDD is complicated and …

[HTML][HTML] Antibodies from a human survivor define sites of vulnerability for broad protection against ebolaviruses

AZ Wec, AS Herbert, CD Murin, EK Nyakatura… - Cell, 2017 - cell.com
Experimental monoclonal antibody (mAb) therapies have shown promise for treatment of
lethal Ebola virus (EBOV) infections, but their species-specific recognition of the viral …

Asiatic acid alleviates myocardial ischemia‐reperfusion injury by inhibiting the ROS‐mediated mitochondria‐dependent apoptosis pathway

C Yi, M Song, L Sun, L Si, D Yu, B Li… - Oxidative Medicine …, 2022 - Wiley Online Library
Myocardial ischemia‐reperfusion injury (MIRI) is a major cause of heart failure in patients
with coronary heart disease (CHD). Mitochondrial dysfunction is the crucial factor of MIRI; …

Protective effects of Poria cocos and its components against cisplatin-induced intestinal injury

YT Zou, J Zhou, CY Wu, W Zhang, H Shen… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Poria cocos (Schw.) Wolf (Poria) is a well-known
traditional medicinal fungus. It has been considered to possess spleen-invigorating (Jianpi) …

Magnetic nanoparticle hyperthermia enhances radiation therapy: A study in mouse models of human prostate cancer

A Attaluri, SK Kandala, M Wabler, H Zhou… - International Journal …, 2015 - Taylor & Francis
Purpose: We aimed to characterise magnetic nanoparticle hyperthermia (mNPH) with
radiation therapy (RT) for prostate cancer. Methods: Human prostate cancer subcutaneous …

Characterization of circRNA-associated-ceRNA networks in a senescence-accelerated mouse prone 8 brain

S Zhang, D Zhu, H Li, H Li, C Feng, W Zhang - Molecular therapy, 2017 - cell.com
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases. Although
many researchers have attempted to explain the origins of AD, developing an effective …