One of the most important achievements of bacteria is its capability to adapt to the changing
conditions of the environment. The competition for nutrients with other microorganisms …

Covering: 2000 to 2018 The antimicrobial activity of many of their natural products has
brought prominence to the Streptomycetaceae, a family of Gram-positive bacteria that …

Phosphorous, in the form of phosphate, is a key element in the nutrition of all living beings.
In nature, it is present in the form of phosphate salts, organophosphates, and phosphonates …

The transcription of amtB in Streptomyces coelicolor has been proposed to be counter-
regulated by GlnR (a global regulator for nitrogen metabolism) and PhoP (a global regulator …

Secondary metabolites are a reliable and very important source of medicinal compounds.
While these molecules have been mined extensively, genome sequencing has suggested …

Bacteria of the Streptomyces genus constitute an authentic biotech gold mine thanks to their
ability to produce a myriad of compounds and enzymes of great interest at various clinical …

Soil dwelling Streptomyces species are faced with large variations in carbon or nitrogen
sources, phosphate, oxygen, iron, sulfur, and other nutrients. These drastic changes in key …

Actinobacteria are producers of a plethora of natural products of agricultural,
biotechnological and clinical importance. In an era where mankind has to deal with rapidly …

Streptomycetes sense and respond to the stress of phosphate starvation via the two-
component PhoR–PhoP signal transduction system. To identify the in vivo targets of PhoP …

Cyclic AMP receptor protein (Crp) is a transcription regulator controlling diverse cellular
processes in many bacteria. In Streptomyces coelicolor, it is well established that Crp plays …