Prevalence of mutations associated with resistance to macrolides and fluoroquinolones in Mycoplasma genitalium: a systematic review and meta-analysis

DA Machalek, Y Tao, H Shilling, JS Jensen… - The lancet infectious …, 2020 - thelancet.com
Background Mycoplasma genitalium is now recognised as an important bacterial sexually
transmitted infection. We summarised data from studies of mutations associated with …

2016 European guideline on Mycoplasma genitalium infections

JS Jensen, M Cusini, M Gomberg… - Journal of the European …, 2016 - Wiley Online Library
Mycoplasma genitalium infection contributes to 10–35% of non‐chlamydial non‐gonococcal
urethritis in men. In women, M. genitalium is associated with cervicitis and pelvic …

2021 European guideline on the management of Mycoplasma genitalium infections

JS Jensen, M Cusini, M Gomberg, H Moi… - Journal of the …, 2022 - Wiley Online Library
Mycoplasma genitalium infection contributes to 10–35% of non‐chlamydial non‐gonococcal
urethritis in men. In women, M. genitalium is associated with cervicitis and pelvic …

Mycoplasma genitalium: from Chrysalis to multicolored butterfly

D Taylor-Robinson, JS Jensen - Clinical microbiology reviews, 2011 - Am Soc Microbiol
The history, replication, genetics, characteristics (both biological and physical), and factors
involved in the pathogenesis of Mycoplasma genitalium are presented. The latter factors …

Antimicrobial-resistant sexually transmitted infections: gonorrhoea and Mycoplasma genitalium

M Unemo, JS Jensen - Nature Reviews Urology, 2017 - nature.com
The emergence of antimicrobial resistance (AMR) is a major concern worldwide and already
compromises treatment effectiveness and control of several bacterial sexually transmitted …

Outcomes of Resistance-guided Sequential Treatment of Mycoplasma genitalium Infections: A Prospective Evaluation

TRH Read, CK Fairley, GL Murray… - Clinical Infectious …, 2019 - academic.oup.com
Background Rising macrolide and quinolone resistance in Mycoplasma genitalium
necessitate new treatment approaches. We evaluated outcomes of sequential antimicrobial …

Resistance to macrolide antibiotics in public health pathogens

C Fyfe, TH Grossman… - Cold Spring …, 2016 - perspectivesinmedicine.cshlp.org
Macrolide resistance mechanisms can be target-based with a change in a 23S ribosomal
RNA (rRNA) residue or a mutation in ribosomal protein L4 or L22 affecting the ribosome's …

Antimicrobial treatment and resistance in sexually transmitted bacterial infections

JS Jensen, M Unemo - Nature Reviews Microbiology, 2024 - nature.com
Sexually transmitted infections (STIs) have been part of human life since ancient times, and
their symptoms affect quality of life, and sequelae are common. Socioeconomic and …

Macrolide Resistance and Azithromycin Failure in a Mycoplasma genitalium–Infected Cohort and Response of Azithromycin Failures to Alternative Antibiotic …

M Bissessor, SN Tabrizi, J Twin, H Abdo… - Clinical infectious …, 2015 - academic.oup.com
Background. Our aim was to determine the efficacy of 1 g azithromycin and alternative
antibiotic regimens in a prospective cohort of Mycoplasma genitalium–infected participants …

Standard treatment regimens for nongonococcal urethritis have similar but declining cure rates: a randomized controlled trial

LE Manhart, CW Gillespie, MS Lowens… - Clinical infectious …, 2013 - academic.oup.com
Background. Azithromycin or doxycycline is recommended for nongonococcal urethritis
(NGU); recent evidence suggests their efficacy has declined. We compared azithromycin …