Integrated bioinformatics analysis to identify alternative therapeutic targets for Alzheimer's disease: insights from a synaptic machinery perspective

H Ceylan - Journal of Molecular Neuroscience, 2022 - Springer
Abstract Alzheimer's disease (AD), the most common type of dementia, is a serious
neurodegenerative disease that has no cure yet, but whose symptoms can be alleviated with …

Neuroprotective potential of tannic acid against neurotoxic outputs of monosodium glutamate in rat cerebral cortex

MS Karagac, H Ceylan - Neurotoxicity Research, 2023 - Springer
Glutamate in monosodium glutamate (MSG), which is widely used in the food industry, has
an important role in major brain functions such as memory, learning, synapse formation, and …

Gold nanoparticles are an immobilization platform for active and stable acetylcholinesterase: Demonstration of a general surface protein functionalization strategy

PR Handali, LJ Webb - ACS Applied Bio Materials, 2022 - ACS Publications
Immobilizing enzymes onto abiological surfaces is a key step for developing protein-based
technologies that can be useful for applications such as biosensors and biofuel cells. A …

The inhibition profile of sesamol against α-glycosidase and acetylcholinesterase enzymes

M Topal - International Journal of Food Properties, 2019 - Taylor & Francis
ABSTRACT Sesamol (1, 3-benzodioxol-5-ol) is found in the oilseed product, sesame. In our
study, the inhibitory effects of sesamol compound on acetylcholinesterase and α …

[HTML][HTML] Expression and epitope prediction of MPT64 recombinant proteins from clinical isolates of Mycobacterium tuberculosis as immunoserodiagnostic candidates

F Fihiruddin, N Inayati, R Jannah, L Unsunnidhal… - Veterinary …, 2022 - ncbi.nlm.nih.gov
Materials and Methods: The polymerase chain reaction (PCR) product of the RV1980c gene
was inserted into the SUMO pET plasmid, which was then transformed into Escherichia coli …

Characterization and kinetic study of the brain and muscle acetylcholinesterase from Danio rerio

CS Marinho, MVF Matias, IGF Brandão… - … and Physiology Part C …, 2019 - Elsevier
Acetylcholinesterase (AChE) plays an important role in the therapy of Alzheimer's disease
and in the detection of pesticides such as organophosphates which are also widely used in …

Soluble and insoluble expression of recombinant human interleukin-2 protein using pET expression vector in Escherichia coli

A Ahmed, NA Fujimura, S Tahir, M Akram… - Preparative …, 2024 - Taylor & Francis
Interleukin-2 has emerged as a potent protein-based drug to treat various cancers, AIDS,
and autoimmune diseases. Despite its immense requirement, the production procedures are …

Cloning and Production of Protease Enzyme from Aeribacillus pallidus P18 Strain.

M Saadati, MO Baltaci, A Adiguzel… - Journal of Pure & …, 2024 - search.ebscohost.com
Proteins are essential for the proper functioning of cells. The techniques of cloning and
protein production have facilitated the advancement of various fields and the creation of …

Cloning, expression and T cell epitope prediction of fbpA and fbpB genes of Mycobacterium tuberculosis clinical isolates

F Mr, WT Artama, T Wibawa… - Journal of microbiology …, 2020 - office2.jmbfs.org
The effective treatment and accurate diagnosis of tuberculosis (TB) are not established yet.
The Bacillus Chalmette-Guerin vaccine did not provide significant results in the prevention of …

Soluble Expression of Recombinant Human Bone Morphogenetic Protein-7 (rhBMP-7) in Escherichia coli Using SUMO Fusion System: Soluble expression of rhBMP …

G Sadipour, A Dugmehchi, Y Talebkhan… - Trends in Peptide and … - journals.sbmu.ac.ir
BMPs belong to transforming growth factor β superfamilies, which their principal role is
inducing bone and cartilage formation at heterotopic and orthotopic sites. Since the …