Role of activating transcription factor 3 and its interacting proteins under physiological and pathological conditions
M Rohini, AH Menon, N Selvamurugan - International journal of biological …, 2018 - Elsevier
Abstract Activating transcription factor 3 (ATF3) is a stress-responsive factor that belongs to
the activator protein 1 (AP-1) family of transcription factors. ATF3 expression is stimulated by …
the activator protein 1 (AP-1) family of transcription factors. ATF3 expression is stimulated by …
Exosomes in bone remodeling and breast cancer bone metastasis
Exosomes are endosome-derived microvesicles that carry cell-specific biological cargo,
such as proteins, lipids, and noncoding RNAs (ncRNAs). They play a key role in bone …
such as proteins, lipids, and noncoding RNAs (ncRNAs). They play a key role in bone …
Extracellular vesicle–packaged CDH11 and ITGA5 induce the premetastatic niche for bone colonization of breast cancer cells
XQ Li, R Zhang, H Lu, XM Yue, YF Huang - Cancer Research, 2022 - AACR
Although most breast cancer metastases in bone cause osteolytic lesions, the osteogenic
niche has commonly been described as an initiator of early-stage bone colonization of …
niche has commonly been described as an initiator of early-stage bone colonization of …
Osteoporosis: Current and emerging therapies targeted to immunological checkpoints
M De Martinis, MM Sirufo… - Current medicinal …, 2020 - ingentaconnect.com
Osteoporosis is a skeletal pathology characterized by compromised bone strength leading
to increased risk of fracture, mainly the spine and hip fractures. Osteoporosis affects more …
to increased risk of fracture, mainly the spine and hip fractures. Osteoporosis affects more …
DNA repair inhibitors: potential targets and partners for targeted radionuclide therapy
H Obata, M Ogawa, MR Zalutsky - Pharmaceutics, 2023 - mdpi.com
The present review aims to explore the potential targets/partners for future targeted
radionuclide therapy (TRT) strategies, wherein cancer cells often are not killed effectively …
radionuclide therapy (TRT) strategies, wherein cancer cells often are not killed effectively …
Syringic acid, a phenolic acid, promotes osteoblast differentiation by stimulation of Runx2 expression and targeting of Smad7 by miR-21 in mouse mesenchymal stem …
B Arumugam, K Balagangadharan… - Journal of cell …, 2018 - Springer
Syringic acid (SA), a phenolic acid, has been used in Chinese and Indian medicine for
treating diabetes but its role in osteogenesis has not yet been investigated. In the present …
treating diabetes but its role in osteogenesis has not yet been investigated. In the present …
Organophosphate ester tri-o-cresyl phosphate interacts with estrogen receptor α in MCF-7 breast cancer cells promoting cancer growth
M Böckers, NW Paul, T Efferth - Toxicology and applied pharmacology, 2020 - Elsevier
Plastic in the ocean degrades to microplastic, thereby enhancing the leaching of
incorporated plasticizers due to the increased particle surface. The uptake of microplastic …
incorporated plasticizers due to the increased particle surface. The uptake of microplastic …
Deposition of calcium in an in vitro model of human breast tumour calcification reveals functional role for ALP activity, altered expression of osteogenic genes and …
S O'Grady, MP Morgan - Scientific reports, 2019 - nature.com
Microcalcifications are vital mammographic indicators contributing to the early detection of
up to 50% of non-palpable tumours and may also be valuable as prognostic markers …
up to 50% of non-palpable tumours and may also be valuable as prognostic markers …
Targeting Breast Cancer: The Familiar, the Emerging, and the Uncharted Territories
H Montazeri Aliabadi, A Manda, R Sidgal, C Chung - Biomolecules, 2023 - mdpi.com
Breast cancer became the most diagnosed cancer in the world in 2020. Chemotherapy is
still the leading clinical strategy in breast cancer treatment, followed by hormone therapy …
still the leading clinical strategy in breast cancer treatment, followed by hormone therapy …
NSDHL promotes triple-negative breast cancer metastasis through the TGFβ signaling pathway and cholesterol biosynthesis
M Chen, Y Zhao, X Yang, Y Zhao, Q Liu, Y Liu… - Breast Cancer Research …, 2021 - Springer
Purpose Metastasis is the main cause of breast cancer mortality. Recent studies have
proved that lipid metabolic reprogramming plays critical roles in breast cancer …
proved that lipid metabolic reprogramming plays critical roles in breast cancer …