Circulating microRNAs: new biomarkers in diagnosis, prognosis and treatment of cancer

A Allegra, A Alonci, S Campo… - International …, 2012 - spandidos-publications.com
MicroRNAs (miRNAs) are small non-coding, endogenous, single-stranded RNAs. MiRNAs
have been implicated in different areas such as the immune response, neural development …

MicroRNA in prostate, bladder, and kidney cancer: a systematic review

JWF Catto, A Alcaraz, AS Bjartell, RDV White… - European urology, 2011 - Elsevier
CONTEXT: MicroRNAs (miRNA) are noncoding RNAs that post-transcriptionally regulate
gene expression. Their altered expression and function have been observed in most …

Comparative analysis of discrete exosome fractions obtained by differential centrifugation

DK Jeppesen, ML Hvam… - Journal of …, 2014 - Taylor & Francis
Background Cells release a mixture of extracellular vesicles, amongst these exosomes, that
differ in size, density and composition. The standard isolation method for exosomes is …

Cellular disposal of miR23b by RAB27-dependent exosome release is linked to acquisition of metastatic properties

MS Ostenfeld, DK Jeppesen, JR Laurberg, AT Boysen… - Cancer research, 2014 - AACR
Exosomes are small secreted vesicles that can transfer their content to recipient cells. In
cancer, exosome secretion has been implicated in tumor growth and metastatic spread. In …

Non-coding RNA in bladder cancer

Y Li, G Li, X Guo, H Yao, G Wang, C Li - Cancer letters, 2020 - Elsevier
Bladder cancer is the tenth most common cancer worldwide and has been associated with
high mortality and morbidity. Although the treatment of bladder cancer is based on well …

MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis

Q Xu, LZ Liu, X Qian, Q Chen, Y Jiang, D Li… - Nucleic acids …, 2012 - academic.oup.com
MiR-145 can regulate cell apoptosis, proliferation, neural development and stem cell
differentiation. Previous studies indicate that miR-145 is downregulated in human colon …

Aberrant expression of microRNAs in bladder cancer

H Yoshino, N Seki, T Itesako, T Chiyomaru… - Nature Reviews …, 2013 - nature.com
MicroRNAs (miRNAs), a class of small noncoding RNAs, regulate protein-coding gene
expression by repressing translation or cleaving RNA transcripts in a sequence-specific …

Salivary micro RNA s in oral cancer

F Zahran, D Ghalwash, O Shaker, K Al‐Johani… - Oral …, 2015 - Wiley Online Library
Objective This study investigated the use of three salivary micro RNA s (mi RNA‐21, mi RNA‐
184, and mi RNA‐145) as possible markers for malignant transformation in oral mucosal …

MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion

HJ Wang, HJ Ruan, XJ He, YY Ma, XT Jiang… - European journal of …, 2010 - Elsevier
MicroRNAs (miRNAs) are short non-coding RNA molecules playing regulatory roles by
repressing translation or cleaving RNA transcripts. Dysregulated expression of miRNAs is …

Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential …

DK Jeppesen, A Nawrocki, SG Jensen, K Thorsen… - …, 2014 - Wiley Online Library
Cancer cells secrete soluble factors and various extracellular vesicles, including exosomes,
into their tissue microenvironment. The secretion of exosomes is speculated to facilitate local …