Circulating microRNAs: new biomarkers in diagnosis, prognosis and treatment of cancer
A Allegra, A Alonci, S Campo… - International …, 2012 - spandidos-publications.com
MicroRNAs (miRNAs) are small non-coding, endogenous, single-stranded RNAs. MiRNAs
have been implicated in different areas such as the immune response, neural development …
have been implicated in different areas such as the immune response, neural development …
MicroRNA in prostate, bladder, and kidney cancer: a systematic review
CONTEXT: MicroRNAs (miRNA) are noncoding RNAs that post-transcriptionally regulate
gene expression. Their altered expression and function have been observed in most …
gene expression. Their altered expression and function have been observed in most …
Comparative analysis of discrete exosome fractions obtained by differential centrifugation
DK Jeppesen, ML Hvam… - Journal of …, 2014 - Taylor & Francis
Background Cells release a mixture of extracellular vesicles, amongst these exosomes, that
differ in size, density and composition. The standard isolation method for exosomes is …
differ in size, density and composition. The standard isolation method for exosomes is …
Cellular disposal of miR23b by RAB27-dependent exosome release is linked to acquisition of metastatic properties
MS Ostenfeld, DK Jeppesen, JR Laurberg, AT Boysen… - Cancer research, 2014 - AACR
Exosomes are small secreted vesicles that can transfer their content to recipient cells. In
cancer, exosome secretion has been implicated in tumor growth and metastatic spread. In …
cancer, exosome secretion has been implicated in tumor growth and metastatic spread. In …
Non-coding RNA in bladder cancer
Bladder cancer is the tenth most common cancer worldwide and has been associated with
high mortality and morbidity. Although the treatment of bladder cancer is based on well …
high mortality and morbidity. Although the treatment of bladder cancer is based on well …
MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis
Q Xu, LZ Liu, X Qian, Q Chen, Y Jiang, D Li… - Nucleic acids …, 2012 - academic.oup.com
MiR-145 can regulate cell apoptosis, proliferation, neural development and stem cell
differentiation. Previous studies indicate that miR-145 is downregulated in human colon …
differentiation. Previous studies indicate that miR-145 is downregulated in human colon …
Aberrant expression of microRNAs in bladder cancer
H Yoshino, N Seki, T Itesako, T Chiyomaru… - Nature Reviews …, 2013 - nature.com
MicroRNAs (miRNAs), a class of small noncoding RNAs, regulate protein-coding gene
expression by repressing translation or cleaving RNA transcripts in a sequence-specific …
expression by repressing translation or cleaving RNA transcripts in a sequence-specific …
Salivary micro RNA s in oral cancer
F Zahran, D Ghalwash, O Shaker, K Al‐Johani… - Oral …, 2015 - Wiley Online Library
Objective This study investigated the use of three salivary micro RNA s (mi RNA‐21, mi RNA‐
184, and mi RNA‐145) as possible markers for malignant transformation in oral mucosal …
184, and mi RNA‐145) as possible markers for malignant transformation in oral mucosal …
MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion
HJ Wang, HJ Ruan, XJ He, YY Ma, XT Jiang… - European journal of …, 2010 - Elsevier
MicroRNAs (miRNAs) are short non-coding RNA molecules playing regulatory roles by
repressing translation or cleaving RNA transcripts. Dysregulated expression of miRNAs is …
repressing translation or cleaving RNA transcripts. Dysregulated expression of miRNAs is …
Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential …
DK Jeppesen, A Nawrocki, SG Jensen, K Thorsen… - …, 2014 - Wiley Online Library
Cancer cells secrete soluble factors and various extracellular vesicles, including exosomes,
into their tissue microenvironment. The secretion of exosomes is speculated to facilitate local …
into their tissue microenvironment. The secretion of exosomes is speculated to facilitate local …