Brain aging mechanisms with mechanical manifestations

Y Blinkouskaya, A Caçoilo, T Gollamudi… - Mechanisms of ageing …, 2021 - Elsevier
Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …

Aging of cerebral white matter

H Liu, Y Yang, Y Xia, W Zhu, RK Leak, Z Wei… - Ageing research …, 2017 - Elsevier
White matter (WM) occupies a large volume of the human cerebrum and is mainly composed
of myelinated axons and myelin-producing glial cells. The myelinated axons within WM are …

Atlasing the frontal lobe connections and their variability due to age and education: a spherical deconvolution tractography study

K Rojkova, E Volle, M Urbanski, F Humbert… - Brain Structure and …, 2016 - Springer
In neuroscience, there is a growing consensus that higher cognitive functions may be
supported by distributed networks involving different cerebral regions, rather than by single …

Hypertension, brain damage and cognitive decline

D Gąsecki, M Kwarciany, W Nyka… - Current hypertension …, 2013 - Springer
Loss of cognitive function is one the most devastating manifestations of ageing and vascular
disease. Cognitive decline is rapidly becoming an important cause of disability worldwide …

High blood pressure and cerebral white matter lesion progression in the general population

BFJ Verhaaren, MW Vernooij, R de Boer, A Hofman… - …, 2013 - Am Heart Assoc
High blood pressure is considered an important risk factor for cerebral white matter lesions
(WMLs) in the aging population. In a longitudinal population-based study of 665 …

Changes in normal-appearing white matter precede development of white matter lesions

M De Groot, BFJ Verhaaren, R De Boer, S Klein… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—It is unknown whether white matter lesions (WML) develop
abruptly in previously normal brain areas, or whether tissue changes are already present …

Homocysteine and age-associated disorders

EA Ostrakhovitch, S Tabibzadeh - Ageing research reviews, 2019 - Elsevier
There are numerous theories of aging, a process which still seems inevitable. Aging leads to
cancer and multi-systemic disorders as well as chronic diseases. Decline in age-associated …

[HTML][HTML] Improving alignment in tract-based spatial statistics: evaluation and optimization of image registration

M De Groot, MW Vernooij, S Klein, MA Ikram, FM Vos… - Neuroimage, 2013 - Elsevier
Anatomical alignment in neuroimaging studies is of such importance that considerable effort
is put into improving the registration used to establish spatial correspondence. Tract-based …

[HTML][HTML] Brain shape changes associated with cerebral atrophy in healthy aging and Alzheimer's disease

Y Blinkouskaya, J Weickenmeier - Frontiers in Mechanical …, 2021 - frontiersin.org
Both healthy and pathological brain aging are characterized by various degrees of cognitive
decline that strongly correlate with morphological changes referred to as cerebral atrophy …

[PDF][PDF] Iäkkäiden kaatumisten ehkäisy

S Pajala - 2012 - julkari.fi
Iäkkäiden kaatumisten ehkäisy-opas kokoaa tietoa ja käytännön työvälineitä kaatumisten
ehkäisyn toteuttamiseksi. Opas perustuu tutkimustietoon sekä kliinisessä käytännössä …