The regulation of body temperature is one of the most critical functions of the nervous
system. Here we review our current understanding of thermoregulation in mammals. We …

Maintenance of a homeostatic body core temperature is a critical brain function
accomplished by a central neural network. This orchestrates a complex behavioral and …

Simple Summary The study of the hypothalamic neuromodulation of thermoregulation offers
broad areas of opportunity with practical applications that are currently being strengthened …

Various environmental stressors, such as extreme temperatures (hot and cold), pathogens,
predators and insufficient food, can threaten life. Remarkable progress has recently been …

Central neural circuits orchestrate a homeostatic repertoire to maintain body temperature
during environmental temperature challenges and to alter body temperature during the …

Body temperature regulation is a fundamental homeostatic function that is governed by the
central nervous system in homeothermic animals, including humans. The central …

While summarizing the current understanding of how body temperature (Tb) is regulated,
this review discusses the recent progress in the following areas: central and peripheral …

Despite affecting millions of individuals, the etiology of hot flushes remains unknown. Here
we review the physiology of hot flushes, CNS pathways regulating heat-dissipation effectors …

Central neural circuits orchestrate the behavioral and autonomic repertoire that maintains
body temperature during environmental temperature challenges and alters body …

Fever is a common symptom of infectious and inflammatory disease. It is well-established
that prostaglandin E2 is the final mediator of fever, which by binding to its EP3 receptor …