Medicinal plants utilized in the management of epilepsy in Ethiopia: ethnobotany, pharmacology and phytochemistry
YS Birhan - Chinese Medicine, 2022 - Springer
Epilepsy is a common central nervous system (CNS) disorder that affects 50 million people
worldwide. Patients with status epilepticus (SE) suffer from devastating comorbidities and a …
worldwide. Patients with status epilepticus (SE) suffer from devastating comorbidities and a …
Herbal medicine for epilepsy seizures in Asia, Africa and Latin America: A systematic review
E Auditeau, F Chassagne, G Bourdy, M Bounlu… - Journal of …, 2019 - Elsevier
Relevance More than 70 million people suffer epilepsy worldwide. Low availability of anti-
epileptic drugs, side-effects and drug-resistant epilepsy affect the quality of life of persons …
epileptic drugs, side-effects and drug-resistant epilepsy affect the quality of life of persons …
In Silico Analysis, Anticonvulsant Activity, and Toxicity Evaluation of Schisandrin B in Zebrafish Larvae and Mice
D Nieoczym, NS Banono, K Stępnik, AA Kaczor… - International Journal of …, 2023 - mdpi.com
The aim of this study is to evaluate the anticonvulsant potential of schisandrin B, a main
ingredient of Schisandra chinensis extracts. Schisandrin B showed anticonvulsant activity in …
ingredient of Schisandra chinensis extracts. Schisandrin B showed anticonvulsant activity in …
Anticonvulsant Activity of Hydro Alcoholic Extract and Solvent Fractions of Biophytum umbraculum Welw. Syn (Oxalidaceae) Root in Mice
N Fisseha, WW Hammeso, D Nureye - Journal of Experimental …, 2022 - Taylor & Francis
Background Scientists and researchers continue to focus on medicinal plants as a potential
source of lead chemicals in the search for and development of new antiepileptic medicines …
source of lead chemicals in the search for and development of new antiepileptic medicines …
Neuroprotective Properties of Oleanolic Acid—Computational-Driven Molecular Research Combined with In Vitro and In Vivo Experiments
K Stępnik, W Kukula-Koch, W Plazinski, M Rybicka… - Pharmaceuticals, 2023 - mdpi.com
Oleanolic acid (OA), as a ubiquitous compound in the plant kingdom, is studied for both its
neuroprotective and neurotoxic properties. The mechanism of acetylcholinesterase (AChE) …
neuroprotective and neurotoxic properties. The mechanism of acetylcholinesterase (AChE) …
Antidepressant-Like Activity of Solvent Fractions of the Root Bark of Carissa spinarum Linn. (Apocynaceae) in Rodents Involves Multiple Signaling Pathways
HS Ali, E Engidawork - Journal of Experimental Pharmacology, 2022 - Taylor & Francis
Background The root bark of Carissa spinarum Linn.(Apocynaceae) is claimed to be used
for the management of depression in Ethiopian folkloric medicine, and the crude extract has …
for the management of depression in Ethiopian folkloric medicine, and the crude extract has …
Evaluation of Anticonvulsant Activity of 80% Methanolic Root Bark Extract and Solvent Fractions of Pentas schimperiana (A. Rich.) Vatke (Rubiaceae) in Swiss Albino …
N Fisseha, W Shibeshi, D Bisrat - … in Pharmacological and …, 2021 - Wiley Online Library
Background. Epilepsy is one of the most common serious neurological disorders,
responsible for substantial morbidity and mortality due to limited efficacy and negative …
responsible for substantial morbidity and mortality due to limited efficacy and negative …
Anti-convulsant effects of scutellarein in a PTZ kindling model in mice
J Duan, J Wang, Q Zhao, D Wu… - Pharmacognosy …, 2024 - journals.sagepub.com
Background: Epilepsy is a chronic neurological condition with various underlying
mechanisms. It is known to affect a multitude of people across the globe, regardless of age …
mechanisms. It is known to affect a multitude of people across the globe, regardless of age …
Phytotherapeutic options for the treatment of epilepsy: pharmacology, targets, and mechanism of action
Epilepsy is one of the most common, severe, chronic, potentially life-shortening neurological
disorders, characterized by a persisting predisposition to generate seizures. It affects more …
disorders, characterized by a persisting predisposition to generate seizures. It affects more …
Molecular and Pharmacokinetic Aspects of the Acetylcholinesterase-Inhibitory Potential of the Oleanane-Type Triterpenes and Their Glycosides
K Stępnik, W Kukula-Koch, W Płaziński - Biomolecules, 2023 - mdpi.com
The acetylcholinesterase-inhibitory potential of the oleanane-type triterpenes and their
glycosides from thebark of Terminalia arjuna (Combreatceae), ie, arjunic acid, arjunolic acid …
glycosides from thebark of Terminalia arjuna (Combreatceae), ie, arjunic acid, arjunolic acid …