Mortality in people with schizophrenia: a systematic review and meta‐analysis of relative risk and aggravating or attenuating factors
CU Correll, M Solmi, G Croatto, LK Schneider… - World …, 2022 - Wiley Online Library
People with schizophrenia die 15‐20 years prematurely. Understanding mortality risk and
aggravating/attenuating factors is essential to reduce this gap. We conducted a systematic …
aggravating/attenuating factors is essential to reduce this gap. We conducted a systematic …
Digital phenotyping in adults with schizophrenia: a narrative review
Abstract Purpose of Review As care for older adult patients with schizophrenia lacks
innovation, technology can help advance the field. Specifically, digital phenotyping, the real …
innovation, technology can help advance the field. Specifically, digital phenotyping, the real …
The future of psychopharmacology: a critical appraisal of ongoing phase 2/3 trials, and of some current trends aiming to de‐risk trial programmes of novel agents
Despite considerable progress in pharmacotherapy over the past seven decades, many
mental disorders remain insufficiently treated. This situation is in part due to the limited …
mental disorders remain insufficiently treated. This situation is in part due to the limited …
Sexual dysfunction in schizophrenia: a systematic review and meta-analysis
T Korchia, V Achour, M Faugere, A Albeash… - JAMA …, 2023 - jamanetwork.com
Importance In individuals with schizophrenia, antipsychotic-induced dysfunctions are
frequent but often underexplored in clinical practice. Objective To synthetize the data of …
frequent but often underexplored in clinical practice. Objective To synthetize the data of …
Pneumonia risk, antipsychotic dosing, and anticholinergic burden in schizophrenia
JJ Luykx, CU Correll, P Manu, A Tanskanen… - JAMA …, 2024 - jamanetwork.com
Importance Antipsychotic drugs (particularly clozapine) have been associated with
pneumonia in observational studies. Despite studies of the associations between …
pneumonia in observational studies. Despite studies of the associations between …
The direct and long-term effects of raloxifene as adjunctive treatment for schizophrenia-spectrum disorders: a double-blind, randomized clinical trial
Background and hypothesis Several studies suggest that raloxifene, a selective estrogen
receptor modulator, improves symptoms and cognition in post-menopausal women with …
receptor modulator, improves symptoms and cognition in post-menopausal women with …
Antipsychotic-induced akathisia in adults with acute schizophrenia: A systematic review and dose-response meta-analysis
Antipsychotic-induced akathisia is severely distressing. We aimed to investigate
relationships between antipsychotic doses and akathisia risk. We searched for randomised …
relationships between antipsychotic doses and akathisia risk. We searched for randomised …
Efficacy and effectiveness of antipsychotics in schizophrenia: network meta-analyses combining evidence from randomised controlled trials and real-world data
Background There is debate about the generalisability of results from randomised clinical
trials (RCTs) to real-world settings. Studying outcomes of treatments for schizophrenia can …
trials (RCTs) to real-world settings. Studying outcomes of treatments for schizophrenia can …
An international research agenda for clozapine-resistant schizophrenia
JJ Luykx, JM Gonzalez-Diaz, TW Guu… - The Lancet …, 2023 - thelancet.com
Treatment-resistant symptoms occur in about a third of patients with schizophrenia and are
associated with a substantial reduction in their quality of life. The development of new …
associated with a substantial reduction in their quality of life. The development of new …
Developing clinical prediction models: A step-by-step guide
Predicting future outcomes of patients is essential to clinical practice, with many prediction
models published each year. Empirical evidence suggests that published studies often have …
models published each year. Empirical evidence suggests that published studies often have …