Preterm brain injury: Germinal matrix–intraventricular hemorrhage and post-hemorrhagic ventricular dilatation

LM Leijser, LS de Vries - Handbook of clinical neurology, 2019 - Elsevier
Germinal matrix hemorrhage and intraventricular hemorrhages (GMH-IVH) remain a
common and clinically significant problem in preterm infants, particularly extremely preterm …

Harnessing the therapeutic potential of the stem cell secretome in neonatal diseases

S Tung, E Delavogia, A Fernandez-Gonzalez… - Seminars in …, 2023 - Elsevier
Preterm birth and intra-partum related complications account for a substantial amount of
mortality and morbidity in the neonatal period despite significant advancements in neonatal …

[HTML][HTML] Stem cell therapy for neonatal hypoxic-ischemic encephalopathy: a systematic review of preclinical studies

I Serrenho, M Rosado, A Dinis, C M. Cardoso… - International Journal of …, 2021 - mdpi.com
Neonatal hypoxic-ischemic encephalopathy (HIE) is an important cause of mortality and
morbidity in the perinatal period. This condition results from a period of ischemia and …

[HTML][HTML] Human pluripotent stem cell-derived ectomesenchymal stromal cells promote more robust functional recovery than umbilical cord-derived mesenchymal …

J Huang, F Yang, Z Ji, J Lin, Z Weng, LL Tsang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Aims: Hypoxic-ischaemic encephalopathy (HIE) is one of the most serious complications in
neonates and infants. Mesenchymal stromal cell (MSC)-based therapy is emerging as a …

Secretome of mesenchymal stem cells and its potential protective effects on brain pathologies

E Baez-Jurado, O Hidalgo-Lanussa… - Molecular …, 2019 - Springer
Previous studies have indicated that mesenchymal stem cells (MSCs) have a fundamental
role in the repair and regeneration of damaged tissues. There is strong evidence showing …

[HTML][HTML] Germinal matrix-intraventricular hemorrhage of the preterm newborn and preclinical models: inflammatory considerations

I Atienza-Navarro, P Alves-Martinez… - International journal of …, 2020 - mdpi.com
The germinal matrix-intraventricular hemorrhage (GM-IVH) is one of the most important
complications of the preterm newborn. Since these children are born at a critical time in …

[HTML][HTML] Dose-dependent effect of intravenous administration of human umbilical cord-derived mesenchymal stem cells in neonatal stroke mice

E Tanaka, Y Ogawa, T Mukai, Y Sato… - Frontiers in …, 2018 - frontiersin.org
Neonatal brain injury induced by stroke causes significant disability, including cerebral
palsy, and there is no effective therapy for stroke. Recently, mesenchymal stem cells (MSCs) …

Umbilical cord-derived mesenchymal stem cells in neurodegenerative disorders: from literature to clinical practice

S Reyhani, B Abbaspanah, SH Mousavi - Regenerative Medicine, 2020 - Future Medicine
Mesenchymal stem cells (MSCs) have provided a promising tool for cell therapy. Umbilical
cord (UC) is one of the best sources of MSCs since its collection is noninvasive, and …

[HTML][HTML] Mesenchymal stromal cells as a potential therapeutic for neurological disorders

T Mukai, A Tojo, T Nagamura-Inoue - Regenerative therapy, 2018 - Elsevier
Several studies have reported that mesenchymal stromal/stem cells (MSCs) restore
neurological damage through their secretion of paracrine factors or their differentiation to …

[HTML][HTML] The immunomodulatory effect of triptolide on mesenchymal stromal cells

H He, A Takahashi, T Mukai, A Hori, M Narita… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are known to have immunosuppressive ability and have
been used in clinical treatment of acute graft-versus-host disease, one of severe …