MYC, a major oncogenic transcription factor, regulates target genes involved in various
pathways such as cell proliferation, metabolism and immune evasion, playing a critical role …

Cell proliferation and function require nutrients, energy, and biosynthesis activity to duplicate
repertoires for each daughter. It is therefore not surprising that tumor microenvironment …

Objective Adaptive rewiring of cancer energy metabolism has received increasing attention.
By binding with LDLs, LDLRs make most of the circulating cholesterol available for cells to …

Colorectal cancer (CRC) is one of the deadliest malignant tumors worldwide and its
prevalence is increasing in South Korea. The efficacy of combined treatment with natural …

Hepatocellular carcinoma (HCC) represents the most important type of liver cancer, the 5-
year survival rate for advanced HCC is 2%. The heterogeneity of HCC makes previous …

Background Hepatocellular carcinoma (HCC) has a poor prognosis and has become the
sixth most common malignancy worldwide due to its high incidence. Advanced approaches …

Recent research has indicated that metabolically related genes play crucial roles in the
pathogenesis of hepatocellular carcinoma (HCC). We evaluated the associations between …

Warburg phenomenon refers to the development of unique metabolic patterns during the
growth of tumor cells. This study stratified gastric cancer into prognostic metabolic …

Background Globally, gastrointestinal (GI) cancer is one of the most prevalent malignant
tumors. However, studies have not established glycolysis-related gene signatures that can …

Background We aimed to provide a new typing method for osteosarcoma (OS) based on
single‐cell RNA sequencing (scRNA‐seq) and bulk RNA‐seq data from the perspective of …