Alcohol use disorder (AUD) is a widespread disease with limited treatment options.
Targeting the neuroimmune system is a new avenue for developing or repurposing effective …

Drinking alcohol, even in moderation, can affect the immune system. Studies have shown
disproportionate effects of alcohol on circulating and tissue-resident myeloid cells …

It is well established that chronic heavy alcohol drinking (CHD) results in significant organ
damage, increased susceptibility to infections, and poor outcomes following injury. In …

Background Whether an association between alcohol consumption and periodontitis exists
is still unclear. This study aimed to assess the association between alcohol consumption …

Alcohol use disorder (AUD) results in increased intestinal permeability, nutrient
malabsorption, and increased risk of colorectal cancer (CRC). Our understanding of the …

The innate immunity has evolved during millions of years, and thus, equivalent or
comparable components are found in most vertebrates, invertebrates, and even plants. It …

Long-term alcohol use causes widespread changes in gene expression in the human brain.
Aberrant gene expression changes likely contribute to the progression from occasional …

A major barrier to remission from an alcohol use disorder (AUD) is the continued risk of
relapse during abstinence. Assessing the neuroadaptations after chronic alcohol and …

Chronic heavy drinking (CHD) of alcohol is a known risk factor for increased susceptibility to
bacterial and viral infection as well as impaired wound healing. Evidence suggests that …

Chronic alcohol drinking is associated with increased susceptibility to viral and bacterial
respiratory pathogens. In this study, we use a rhesus macaque model of voluntary ethanol …