Therapeutic oxygen delivery by perfluorocarbon-based colloids

MP Krafft, JG Riess - Advances in colloid and interface science, 2021 - Elsevier
After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …

Phase‐shift, stimuli‐responsive perfluorocarbon nanodroplets for drug delivery to cancer

N Rapoport - Wiley Interdisciplinary Reviews: Nanomedicine …, 2012 - Wiley Online Library
This review focuses on phase‐shift perfluorocarbon nanoemulsions whose action depends
on an ultrasound‐triggered phase shift from a liquid to gas state. For drug‐loaded …

Doxorubicin as a molecular nanotheranostic agent: effect of doxorubicin encapsulation in micelles or nanoemulsions on the ultrasound-mediated intracellular delivery …

P Mohan, N Rapoport - Molecular pharmaceutics, 2010 - ACS Publications
Doxorubicin (DOX) is one of the most commonly used chemotherapeutic drugs and is a
popular research tool due to the inherent fluorescence of the DOX molecule. After DOX …

Formulation and acoustic studies of a new phase-shift agent for diagnostic and therapeutic ultrasound

PS Sheeran, S Luois, PA Dayton, TO Matsunaga - Langmuir, 2011 - ACS Publications
Recent efforts in the area of acoustic droplet vaporization with the objective of designing
extravascular ultrasound contrast agents has led to the development of stabilized, lipid …

Design of ultrasonically-activatable nanoparticles using low boiling point perfluorocarbons

PS Sheeran, SH Luois, LB Mullin, TO Matsunaga… - Biomaterials, 2012 - Elsevier
Recently, an interest has developed in designing biomaterials for medical ultrasonics that
can provide the acoustic activity of microbubbles, but with improved stability in vivo and a …

Phase-change contrast agents for imaging and therapy

PS Sheeran, PA Dayton - Current pharmaceutical design, 2012 - ingentaconnect.com
Phase-change contrast agents (PCCAs) for ultrasound-based applications have resulted in
novel ways of approaching diagnostic and therapeutic techniques beyond what is possible …

Gravity-driven microfluidic particle sorting device with hydrodynamic separation amplification

D Huh, JH Bahng, Y Ling, HH Wei… - Analytical …, 2007 - ACS Publications
This paper describes a simple microfluidic sorting system that can perform size profiling and
continuous mass-dependent separation of particles through combined use of gravity (1 g) …

Decafluorobutane as a phase-change contrast agent for low-energy extravascular ultrasonic imaging

PS Sheeran, VP Wong, S Luois, RJ McFarland… - Ultrasound in medicine …, 2011 - Elsevier
Currently available microbubbles used for ultrasound imaging and therapeutics are limited
to intravascular space due to their size distribution in the micron range. Phase-change …

The role of inertial cavitation in acoustic droplet vaporization

ML Fabiilli, KJ Haworth, NH Fakhri… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
The vaporization of a superheated droplet emulsion into gas bubbles using ultrasound-
termed acoustic droplet vaporization (ADV)-has potential therapeutic applications in …

On the acoustic vaporization of micrometer-sized droplets

OD Kripfgans, ML Fabiilli, PL Carson… - The Journal of the …, 2004 - pubs.aip.org
This paper examines the vaporization of individual dodecafluoropentane droplets by the
application of single ultrasonic tone bursts. High speed video microscopy was used to …