Plasmodium falciparum resistance to chloroquine, the former gold standard antimalarial
drug, is mediated primarily by mutant forms of the chloroquine resistance transporter …

Leishmaniases remain a major public health problem today despite the vast amount of
research conducted on Leishmania pathogens. The biological model is genetically and …

Summary Background Artemisinin-resistant Plasmodium falciparum has been reported in
Pailin, western Cambodia, detected as a slow parasite clearance rate in vivo. Emergence of …

The current epidemic of artemisinin resistant Plasmodium falciparum in Southeast Asia is
the result of a soft selective sweep involving at least 20 independent kelch13 mutations. In a …

The var gene encoded hyper-variable Plasmodium falciparum erythrocyte membrane
protein 1 (PfEMP1) family mediates cytoadhesion of infected erythrocytes to human …

The Plasmodium falciparum chloroquine resistance transporter (PfCRT) is a key contributor
to multidrug resistance and is also essential for the survival of the malaria parasite, yet its …

Background An assessment of the correlation between anti-malarial treatment outcome and
molecular markers would improve the early detection and monitoring of drug resistance by …

Genetic variation allows the malaria parasite Plasmodium falciparum to overcome
chemotherapeutic agents, vaccines and vector control strategies and remain a leading …

A small number of clonal lineages dominates the global population structure of methicillin-
resistant Staphylococcus aureus (MRSA), resulting in the concept that MRSA has emerged …

For reasons that remain unknown, the Plasmodium falciparum genome has an exceptionally
high AT content compared to other Plasmodium species and eukaryotes in general-nearly …