Enzymes, In Vivo Biocatalysis, and Metabolic Engineering for Enabling a Circular Economy and Sustainability
Since the industrial revolution, the rapid growth and development of global industries have
depended largely upon the utilization of coal-derived chemicals, and more recently, the …
depended largely upon the utilization of coal-derived chemicals, and more recently, the …
Role of zinc in immune system and anti-cancer defense mechanisms
D Skrajnowska, B Bobrowska-Korczak - Nutrients, 2019 - mdpi.com
The human body cannot store zinc reserves, so a deficiency can arise relatively quickly, eg,
through an improper diet. Severe zinc deficiency is rare, but mild deficiencies are common …
through an improper diet. Severe zinc deficiency is rare, but mild deficiencies are common …
Scalable biocatalytic C–H oxyfunctionalization reactions
S Chakrabarty, Y Wang, JC Perkins… - Chemical Society …, 2020 - pubs.rsc.org
Catalytic C–H oxyfunctionalization reactions have garnered significant attention in recent
years with their ability to streamline synthetic routes toward complex molecules …
years with their ability to streamline synthetic routes toward complex molecules …
Monooxygenation of aromatic compounds by flavin‐dependent monooxygenases
P Chenprakhon, T Wongnate, P Chaiyen - Protein Science, 2019 - Wiley Online Library
Many flavoenzymes catalyze hydroxylation of aromatic compounds especially phenolic
compounds have been isolated and characterized. These enzymes can be classified as …
compounds have been isolated and characterized. These enzymes can be classified as …
Biotransformation of plant‐derived phenolic acids
R Tinikul, P Chenprakhon, S Maenpuen… - Biotechnology …, 2018 - Wiley Online Library
Phenolic acids are abundant biomass feedstock that can be derived from the processing of
lignin or other byproducts from agro‐industrial waste. Although phenolic acids such as p …
lignin or other byproducts from agro‐industrial waste. Although phenolic acids such as p …
Oxygenating biocatalysts for hydroxyl functionalisation in drug discovery and development
SN Charlton, MA Hayes - ChemMedChem, 2022 - Wiley Online Library
C− H oxyfunctionalisation remains a distinct challenge for synthetic organic chemists.
Oxygenases and peroxygenases (grouped here as “oxygenating biocatalysts”) catalyse the …
Oxygenases and peroxygenases (grouped here as “oxygenating biocatalysts”) catalyse the …
Engineering a prokaryotic non-P450 hydroxylase for 3′-hydroxylation of flavonoids
Plant-derived cytochrome P450-dependent flavonoid 3′-hydroxylases are the rate-limiting
enzymes in flavonoid biosynthesis. In this study, the large component (HpaB) of a …
enzymes in flavonoid biosynthesis. In this study, the large component (HpaB) of a …
Kinetic mechanism of the dechlorinating flavin-dependent monooxygenase HadA
P Pimviriyakul, K Thotsaporn, J Sucharitakul… - Journal of Biological …, 2017 - ASBMB
The accumulation of chlorophenols (CPs) in the environment, due to their wide use as
agrochemicals, has become a serious environmental problem. These organic halides can …
agrochemicals, has become a serious environmental problem. These organic halides can …
Engineering budding yeast for the production of coumarins from lignin
CH Zhao, RK Zhang, B Qiao, BZ Li, YJ Yuan - Biochemical Engineering …, 2020 - Elsevier
As an important renewable resource, lignin has been found difficult to utilize due to its
intrinsic heterogeneity. To meet the increasing demand for lignin valorization, in this study …
intrinsic heterogeneity. To meet the increasing demand for lignin valorization, in this study …
Sustainable biosynthetic pathways to value-added bioproducts from hydroxycinnamic acids
R Tramontina, I Ciancaglini, EKB Roman… - Applied microbiology …, 2023 - Springer
The biorefinery concept, in which biomass is utilized for the production of fuels and
chemicals, emerges as an eco-friendly, cost-effective, and renewable alternative to …
chemicals, emerges as an eco-friendly, cost-effective, and renewable alternative to …