Oleuropein counteracts both the proliferation and migration of intra-and extragonadal seminoma cells
S Bossio, A Perri, R Malivindi, F Giordano, V Rago… - Nutrients, 2022 - mdpi.com
Recent and growing literature has reported that oleuropein (OLE), the main polyphenol in
olive leaf extract, inhibits tumor cell proliferation and reduces the invasiveness properties of …
olive leaf extract, inhibits tumor cell proliferation and reduces the invasiveness properties of …
Pituitary tumor‑transforming gene 1 regulates the senescence and apoptosis of oral squamous cell carcinoma in a p21‑dependent DNA damage response manner
S Park, S Kim, MY Kim, SS Lee… - Oncology …, 2024 - spandidos-publications.com
Pituitary tumor-transforming gene 1 (PTTG1), also known as securin, is a proto-oncogene
involved in the development of various cancers by promoting cell proliferation and mobility …
involved in the development of various cancers by promoting cell proliferation and mobility …
PTTG1 enhances oncolytic adenovirus 5 entry into pancreatic adenocarcinoma cells by increasing CXADR expression
L Long, J Gao, R Zhang - Viruses, 2023 - mdpi.com
Pituitary tumor-transforming gene 1 (PTTG1) is overexpressed in various types of tumors
and functions as an oncogene; it could also be a potential target in tumor therapy …
and functions as an oncogene; it could also be a potential target in tumor therapy …
PTTG1/ZEB1 axis regulates E-cadherin expression in human seminoma
E Teveroni, F Di Nicuolo, E Vergani, G Bianchetti… - Cancers, 2022 - mdpi.com
Simple Summary Seminoma represents one of the most common neoplasms in Caucasian
males between 15 and 40 years old. The molecular pathways underlying its clinical …
males between 15 and 40 years old. The molecular pathways underlying its clinical …
[HTML][HTML] Multi-omics Analysis of the oncogenic value of pituitary tumor-transforming gene 1 (PTTG1) in human cancers
L Wang, X Liu - Frontiers in Bioscience-Landmark, 2024 - imrpress.com
Background: The pituitary tumor-transforming gene 1 (PTTG1), also recognized as securin,
plays a crucial role in diverse biological processes, such as restraining sister chromatid …
plays a crucial role in diverse biological processes, such as restraining sister chromatid …
SPTBN1 Mediates the Cytoplasmic Constraint of PTTG1, Impairing Its Oncogenic Activity in Human Seminoma
E Teveroni, F Di Nicuolo, E Vergani, A Oliva… - International Journal of …, 2023 - mdpi.com
Seminoma is the most common testicular cancer. Pituitary tumor-transforming gene 1
(PTTG1) is a securin showing oncogenic activity in several tumors. We previously …
(PTTG1) is a securin showing oncogenic activity in several tumors. We previously …
Molecular feature-based classification of retroperitoneal liposarcoma: a prospective cohort study
M Xiao, X Li, F Bu, S Ma, X Yang, J Chen, Y Zhao… - MedRxiv, 2024 - medrxiv.org
Background: Retroperitoneal liposarcoma (RPLS) is a critical malignant disease with
various clinical outcomes. However, the molecular heterogeneity of RPLS was poorly …
various clinical outcomes. However, the molecular heterogeneity of RPLS was poorly …
Elevated PTTG1 predicts poor prognosis in kidney renal clear cell carcinoma and correlates with immunity
X Zhang, H Ji, Y Huang, B Zhu, Q Xing - Heliyon, 2023 - cell.com
Background PTTG1 has been reported to be linked with the prognosis and progression of
various cancers, including kidney renal clear cell carcinoma (KIRC). In this article, we mainly …
various cancers, including kidney renal clear cell carcinoma (KIRC). In this article, we mainly …
Expression of CD44 is associated with aggressiveness in seminomas
Background Testicular germ cell tumors (TGCTs) exhibit diverse biological and pathological
features and are divided in two main types, seminomas and nonseminomatous germ cell …
features and are divided in two main types, seminomas and nonseminomatous germ cell …
Pituitary tumor transforming gene 1 promotes proliferation and malignant phenotype in osteosarcoma via NF-κB signaling
X Hu, F Yang, H Mei - Journal of Orthopaedic Science, 2024 - Elsevier
Background Pituitary tumor transforming gene (PTTG) is an oncogene reported to be
actively promotes tumorigenesis in multiple tumors. Osteosarcoma (OS) is the most common …
actively promotes tumorigenesis in multiple tumors. Osteosarcoma (OS) is the most common …