[HTML][HTML] The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infections
Emerging evidence highlights the multifaceted roles of the RNA epitranscriptome during
viral infections. By modulating the modification landscape of viral and host RNAs, viruses …
viral infections. By modulating the modification landscape of viral and host RNAs, viruses …
[HTML][HTML] The regulation of antiviral innate immunity through non-m6A RNA modifications
The post-transcriptional RNA modifications impact the dynamic regulation of gene
expression in diverse biological and physiological processes. Host RNA modifications play …
expression in diverse biological and physiological processes. Host RNA modifications play …
[HTML][HTML] Transcriptomic Signatures of Zika Virus Infection in Patients and a Cell Culture Model
G Berglund, CD Lennon, P Badu, JA Berglund… - Microorganisms, 2024 - mdpi.com
Zika virus (ZIKV), a re-emerging flavivirus, is associated with devasting developmental and
neurological disease outcomes particularly in infants infected in utero. Towards …
neurological disease outcomes particularly in infants infected in utero. Towards …
The landscape of differential splicing and transcript alternations in severe COVID‐19 infection
Viral infections can modulate the widespread alternations of cellular splicing, favouring viral
replication within the host cells by overcoming host immune responses. However, how …
replication within the host cells by overcoming host immune responses. However, how …
[HTML][HTML] COVIDanno, COVID-19 annotation in human
Y Feng, M Yang, Z Fan, W Zhao, P Kim… - Frontiers in …, 2023 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of
coronavirus disease 19 (COVID-19), has caused a global health crisis. Despite ongoing …
coronavirus disease 19 (COVID-19), has caused a global health crisis. Despite ongoing …
[HTML][HTML] CASA: a comprehensive database resource for the COVID-19 Alternative Splicing Atlas
Y Chen, G Wang, J Li, L Xia, L Zhu, W Li, Q Luo… - Journal of Translational …, 2022 - Springer
Background As a key process in transcriptional regulatory mechanisms, alternative splicing
(AS) plays a crucial role in maintaining the diversity of RNA and protein expression, and …
(AS) plays a crucial role in maintaining the diversity of RNA and protein expression, and …
All differential on the splicing front: Host alternative splicing alters the landscape of virus-host conflict
JT Mann, BA Riley, SF Baker - Seminars in Cell & Developmental Biology, 2023 - Elsevier
Alternative RNA splicing is a co-transcriptional process that richly increases proteome
diversity, and is dynamically regulated based on cell species, lineage, and activation state …
diversity, and is dynamically regulated based on cell species, lineage, and activation state …
[HTML][HTML] Zika virus infection in a cell culture model reflects the transcriptomic signatures in patients
G Berglund, CD Lennon, P Badu, JA Berglund… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Zika virus (ZIKV), a re-emerging flavivirus, is associated with devasting developmental and
neurological disease outcomes particularly in infants infected in utero. Towards …
neurological disease outcomes particularly in infants infected in utero. Towards …
The leader RNA of SARS-CoV-2 sequesters polypyrimidine tract binding protein (PTBP1) and influences pre-mRNA splicing in infected cells
NH Altina, DG Maranon, JR Anderson, MK Donaldson… - Virology, 2024 - Elsevier
The large amount of viral RNA produced during infections has the potential to interact with
and effectively sequester cellular RNA binding proteins, thereby influencing aspects of post …
and effectively sequester cellular RNA binding proteins, thereby influencing aspects of post …
An algorithmic framework for isoform-specific functional analysis
G Karlebach, L Carmody, JC Sundaramurthi… - Biorxiv, 2022 - biorxiv.org
Gene Ontology (GO) overrepresentation analysis characterizes the biological mechanisms
common to sets of differentially expressed genes identified by high-throughput experiments …
common to sets of differentially expressed genes identified by high-throughput experiments …