[HTML][HTML] Corneal endothelial dysfunction: Evolving understanding and treatment options

MO Price, JS Mehta, UV Jurkunas… - Progress in retinal and eye …, 2021 - Elsevier
The cornea is exquisitely designed to protect the eye while transmitting and focusing
incoming light. Precise control of corneal hydration by the endothelial cell layer that lines the …

Fuchs endothelial corneal dystrophy: The vicious cycle of Fuchs pathogenesis

SO Tone, V Kocaba, M Böhm, A Wylegala… - Progress in Retinal and …, 2021 - Elsevier
Fuchs endothelial corneal dystrophy (FECD) is the most common primary corneal
endothelial dystrophy and the leading indication for corneal transplantation worldwide …

Descemetorhexis without grafting for Fuchs endothelial dystrophy—supplementation with topical ripasudil

G Moloney, C Petsoglou, M Ball, Y Kerdraon… - Cornea, 2017 - journals.lww.com
Purpose: To report the safety and efficacy of descemetorhexis without grafting as a primary
intervention in Fuchs dystrophy, and the use of a ROCK inhibitor, ripasudil as a salvage …

Use of topical rho kinase inhibitors in the treatment of Fuchs dystrophy after Descemet stripping only

MS Macsai, M Shiloach - Cornea, 2019 - journals.lww.com
Purpose: Fuchs corneal dystrophy (FD) is a common cause of endothelial keratoplasty.
Recently, a series of FD cases treated with Descemet stripping only (DSO) demonstrated …

Treatment of Fuchs endothelial dystrophy by Descemet stripping without endothelial keratoplasty

DS Borkar, P Veldman, KA Colby - Cornea, 2016 - journals.lww.com
Purpose: To evaluate the effect of deliberate removal of the central Descemet membrane on
endothelial function and morphology in patients with Fuchs endothelial dystrophy (FED) and …

[HTML][HTML] Approaches for corneal endothelium regenerative medicine

P Catala, G Thuret, H Skottman, JS Mehta… - Progress in retinal and …, 2022 - Elsevier
The state of the art therapy for treating corneal endothelial disease is transplantation.
Advances in the reproducibility and accessibility of surgical techniques are increasing the …

Fuchs endothelial corneal dystrophy: clinical, genetic, pathophysiologic, and therapeutic aspects

M Matthaei, A Hribek, T Clahsen… - Annual review of …, 2019 - annualreviews.org
Fuchs endothelial corneal dystrophy (FECD) is a bilateral corneal endothelial disorder and
the most common cause of corneal transplantation worldwide. Professor Ernst Fuchs …

Descemet's stripping without endothelial keratoplasty

D Garcerant, N Hirnschall, N Toalster… - Current opinion in …, 2019 - journals.lww.com
Descemet's stripping without endothelial keratoplasty : Current Opinion in Ophthalmology
Descemet's stripping without endothelial keratoplasty : Current Opinion in Ophthalmology …

Application of Rho kinase inhibitors for the treatment of corneal endothelial diseases

N Okumura, S Kinoshita, N Koizumi - Journal of ophthalmology, 2017 - Wiley Online Library
ROCK (Rho kinase) signaling regulates a wide spectrum of fundamental cellular events and
is involved in a variety of pathological conditions. It has therefore attracted research interest …

[HTML][HTML] A review of the evidence for in vivo corneal endothelial regeneration

B Van den Bogerd, SN Dhubhghaill, C Koppen… - Survey of …, 2018 - Elsevier
Human corneal endothelium has long been thought to be a nonmitotic cell layer with no
endogenous reparative potential. Pathologies that damage endothelial function result in …