Branched chain amino acids

M Neinast, D Murashige, Z Arany - Annual review of physiology, 2019 - annualreviews.org
Branched chain amino acids (BCAAs) are building blocks for all life-forms. We review here
the fundamentals of BCAA metabolism in mammalian physiology. Decades of studies have …

Branched-chain amino acids in health and disease: metabolism, alterations in blood plasma, and as supplements

M Holeček - Nutrition & metabolism, 2018 - Springer
Branched-chain amino acids (BCAAs; valine, leucine, and isoleucine) are essential amino
acids with protein anabolic properties, which have been studied in a number of muscle …

[HTML][HTML] Impacts of essential amino acids on energy balance

F Xiao, F Guo - Molecular metabolism, 2022 - Elsevier
Background Obesity develops due to an imbalance in energy homeostasis, wherein energy
intake exceeds energy expenditure. Accumulating evidence shows that manipulations of …

Applications for α-lactalbumin in human nutrition

DK Layman, B Lönnerdal, JD Fernstrom - Nutrition reviews, 2018 - academic.oup.com
Abstract α-Lactalbumin is a whey protein that constitutes approximately 22% of the proteins
in human milk and approximately 3.5% of those in bovine milk. Within the mammary gland, α …

Flavonoids, dairy foods, and cardiovascular and metabolic health: a review of emerging biologic pathways

D Mozaffarian, JHY Wu - Circulation research, 2018 - Am Heart Assoc
A growing body of nutritional science highlights the complex mechanisms and pleiotropic
pathways of cardiometabolic effects of different foods. Among these, some of the most …

Gut microbiota as the link between elevated BCAA serum levels and insulin resistance

J Gojda, M Cahova - Biomolecules, 2021 - mdpi.com
The microbiota-harboring human gut is an exquisitely active ecosystem that has evolved in a
constant symbiosis with the human host. It produces numerous compounds depending on its …

Role of branched-chain amino acid metabolism in type 2 diabetes, obesity, cardiovascular disease and non-alcoholic fatty liver disease

P Cuomo, R Capparelli, A Iannelli… - International journal of …, 2022 - mdpi.com
Branched-chain amino acids (BCAAs) include leucine, isoleucine, and valine. Mammalians
cannot synthesize these amino acids de novo and must acquire them through their diet …

Cheese whey processing: integrated biorefinery concepts and emerging food applications

IK Lappa, A Papadaki, V Kachrimanidou, A Terpou… - Foods, 2019 - mdpi.com
Cheese whey constitutes one of the most polluting by-products of the food industry, due to its
high organic load. Thus, in order to mitigate the environmental concerns, a large number of …

Branched chain amino acids in metabolic disease

Z Arany, M Neinast - Current Diabetes Reports, 2018 - Springer
Abstract Purpose of Review Elevations in circulating branched chain amino acids (BCAAs)
have gained attention as potential contributors to the development of insulin resistance and …

The relationship between branched‐chain amino acid related metabolomic signature and insulin resistance: a systematic review

X Zhao, Q Han, Y Liu, C Sun, X Gang… - Journal of diabetes …, 2016 - Wiley Online Library
Recent studies have shown the positive association between increased circulating BCAAs
(valine, leucine, and isoleucine) and insulin resistance (IR) in obese or diabetic patients …