Post-traumatic stress disorder (PTSD) is a maladaptive and debilitating psychiatric disorder,
characterized by re-experiencing, avoidance, negative emotions and thoughts, and …

Post-traumatic stress disorder (PTSD) is a prevalent, debilitating and sometimes deadly
consequence of exposure to severe psychological trauma. Although effective treatments …

Progress in clinical and affective neuroscience is redefining psychiatric illness as
symptomatic expression of cellular/molecular dysfunctions in specific brain circuits. Post …

We review recent work on the role of intrinsic amygdala networks in the regulation of
classically conditioned defensive behaviors, commonly known as conditioned fear. These …

Preclinical and clinical studies implicate endocannabinoids (eCBs) in fear extinction, but the
underlying neural circuit basis of these actions is unclear. Here, we employed in vivo …

Recent years have seen increased interest in psychopathologies related to trauma
exposure. Specifically, there has been a growing awareness to posttraumatic stress disorder …

Pathological fear and anxiety are highly debilitating and, despite considerable advances in
psychotherapy and pharmacotherapy they remain insufficiently treated in many patients with …

The acquisition of fear associative memory requires brain processes of coordinated neural
activity within the amygdala, prefrontal cortex (PFC), hippocampus, thalamus and brainstem …

Basal amygdala (BA) neurons guide associative learning via acquisition of responses to
stimuli that predict salient appetitive or aversive outcomes. We examined the learning-and …

Threat processing is central to understanding debilitating fear-and trauma-related disorders
such as posttraumatic stress disorder (PTSD). Progress has been made in understanding …