Membrane targeting cationic antimicrobial peptides
Many short cationic peptides are amphiphilic and are often termed antimicrobial peptides
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …
From antimicrobial to anticancer peptides. A review
D Gaspar, AS Veiga, MARB Castanho - Frontiers in microbiology, 2013 - frontiersin.org
Antimicrobial peptides (AMPs) are part of the innate immune defense mechanism of many
organisms. Although AMPs have been essentially studied and developed as potential …
organisms. Although AMPs have been essentially studied and developed as potential …
Multifunctional antimicrobial biometallohydrogels based on amino acid coordinated self‐assembly
There is a real need for new antibiotics against self‐evolving bacteria. One option is to use
biofriendly broad‐spectrum and mechanically tunable antimicrobial hydrogels that can …
biofriendly broad‐spectrum and mechanically tunable antimicrobial hydrogels that can …
Treatment of Superbug Infection through a Membrane‐Disruption and Immune‐Regulation Cascade Effect Based on Supramolecular Peptide Hydrogels
Infections from antimicrobial resistant pathogens have been considered as lethal threats to
human health if antibiotic treatments become ineffective. Antimicrobial peptides (AMPs) …
human health if antibiotic treatments become ineffective. Antimicrobial peptides (AMPs) …
Reversible thermoresponsive peptide–PNIPAM hydrogels for controlled drug delivery
Mixed thermoreversible gels were successfully fabricated by the addition of a
thermosensitive polymer, poly (N-isopropylacrylamide)(PNIPAM), to fibrillar nanostructures …
thermosensitive polymer, poly (N-isopropylacrylamide)(PNIPAM), to fibrillar nanostructures …
Surfactant-like peptides: From molecular design to controllable self-assembly with applications
The diversity of naturally occurring amino acids endows even a very short peptide with an
incredible range of sequences, nanostructures and properties. Short peptide sequences …
incredible range of sequences, nanostructures and properties. Short peptide sequences …
Current scenario of peptide-based drugs: the key roles of cationic antitumor and antiviral peptides
KCL Mulder, LA Lima, VJ Miranda, SC Dias… - Frontiers in …, 2013 - frontiersin.org
Cationic antimicrobial peptides (AMPs) and host defense peptides (HDPs) show vast
potential as peptide-based drugs. Great effort has been made in order to exploit their …
potential as peptide-based drugs. Great effort has been made in order to exploit their …
Improved prediction and characterization of anticancer activities of peptides using a novel flexible scoring card method
P Charoenkwan, W Chiangjong, VS Lee… - Scientific reports, 2021 - nature.com
As anticancer peptides (ACPs) have attracted great interest for cancer treatment, several
approaches based on machine learning have been proposed for ACP identification …
approaches based on machine learning have been proposed for ACP identification …
Tuning the biological activity profile of antibacterial polymers via subunit substitution pattern
R Liu, X Chen, S Chakraborty, JJ Lemke… - Journal of the …, 2014 - ACS Publications
Binary nylon-3 copolymers containing cationic and hydrophobic subunits can mimic the
biological properties of host-defense peptides, but relationships between composition and …
biological properties of host-defense peptides, but relationships between composition and …
Structural disruptions of the outer membranes of gram-negative bacteria by rationally designed amphiphilic antimicrobial peptides
Gram-negative bacteria are covered by both an inner cytoplasmic membrane (IM) and an
outer membrane (OM). Antimicrobial peptides (AMPs) must first permeate through the OM …
outer membrane (OM). Antimicrobial peptides (AMPs) must first permeate through the OM …