Structural variants and speciation: multiple processes at play
Research on the genomic architecture of speciation has increasingly revealed the
importance of structural variants (SVs) that affect the presence, abundance, position, and/or …
importance of structural variants (SVs) that affect the presence, abundance, position, and/or …
Copy number variation in the cattle genome
GE Liu, DM Bickhart - Functional & integrative genomics, 2012 - Springer
Copy number variations (CNVs) are gains and losses of genomic sequence greater than 50
bp between two individuals of a species. While single nucleotide polymorphisms (SNPs) are …
bp between two individuals of a species. While single nucleotide polymorphisms (SNPs) are …
Harnessing the power of multi‐omics data for predicting climate change response
KKS Layton, IR Bradbury - Journal of Animal Ecology, 2022 - Wiley Online Library
Predicting how species will respond to future climate change is of central importance in the
midst of the global biodiversity crisis, and recent work has demonstrated the utility of …
midst of the global biodiversity crisis, and recent work has demonstrated the utility of …
Gene copy number is differentially regulated in a multipartite virus
A Sicard, M Yvon, T Timchenko, B Gronenborn… - Nature …, 2013 - nature.com
Multipartite viruses have a genome divided into several nucleic acid segments, each
encapsidated separately. An evident cost for these viral systems, particularly if some …
encapsidated separately. An evident cost for these viral systems, particularly if some …
Population-genetic properties of differentiated copy number variations in cattle
L Xu, Y Hou, DM Bickhart, Y Zhou, EHA Hay, J Song… - Scientific reports, 2016 - nature.com
While single nucleotide polymorphism (SNP) is typically the variant of choice for population
genetics, copy number variation (CNV) which comprises insertion, deletion and duplication …
genetics, copy number variation (CNV) which comprises insertion, deletion and duplication …
Extensive copy-number variation of young genes across stickleback populations
Duplicate genes emerge as copy-number variations (CNVs) at the population level, and
remain copy-number polymorphic until they are fixed or lost. The successful establishment of …
remain copy-number polymorphic until they are fixed or lost. The successful establishment of …
Population differentiated copy number variation of Bos taurus, Bos indicus and their African hybrids
Background CNV comprises a large proportion in cattle genome and is associated with
various traits. However, there were few population-scale comparison studies on cattle CNV …
various traits. However, there were few population-scale comparison studies on cattle CNV …
Population structure shapes copy number variation in malaria parasites
IH Cheeseman, B Miller, JC Tan, A Tan… - Molecular biology …, 2016 - academic.oup.com
If copy number variants (CNVs) are predominantly deleterious, we would expect them to be
more efficiently purged from populations with a large effective population size (N e) than …
more efficiently purged from populations with a large effective population size (N e) than …
A population genomic characterization of copy number variation in the opportunistic fungal pathogen Aspergillus fumigatus
S Zhao, JG Gibbons - PLoS One, 2018 - journals.plos.org
Aspergillus fumigatus is a potentially deadly opportunistic fungal pathogen. Molecular
studies have shaped our understanding of the genes, proteins, and molecules that …
studies have shaped our understanding of the genes, proteins, and molecules that …
Copy number variation contributes to cryptic genetic variation in outbreak lineages of Cryptococcus gattii from the North American Pacific Northwest
Abstract Background Copy number variants (CNVs) are a class of structural variants (SVs)
and are defined as fragments of DNA that are present at variable copy number in …
and are defined as fragments of DNA that are present at variable copy number in …