[HTML][HTML] A review of transformers in drug discovery and beyond
Transformer models have emerged as pivotal tools within the realm of drug discovery,
distinguished by their unique architectural features and exceptional performance in …
distinguished by their unique architectural features and exceptional performance in …
Application of deep learning in cancer epigenetics through DNA methylation analysis
DNA methylation is a fundamental epigenetic modification involved in various biological
processes and diseases. Analysis of DNA methylation data at a genome-wide and high …
processes and diseases. Analysis of DNA methylation data at a genome-wide and high …
Deep learning methods for omics data imputation
Simple Summary Missing values are common in omics data and can arise from various
causes. Imputation approaches offer a different means of handling missing data instead of …
causes. Imputation approaches offer a different means of handling missing data instead of …
Multi-scale attention flow for probabilistic time series forecasting
The probability prediction of multivariate time series is a notoriously challenging but practical
task. On the one hand, the challenge is how to effectively capture the cross-series …
task. On the one hand, the challenge is how to effectively capture the cross-series …
MetaTransformer: deep metagenomic sequencing read classification using self-attention models
A Wichmann, E Buschong, A Müller… - NAR Genomics and …, 2023 - academic.oup.com
Deep learning has emerged as a paradigm that revolutionizes numerous domains of
scientific research. Transformers have been utilized in language modeling outperforming …
scientific research. Transformers have been utilized in language modeling outperforming …
Recall DNA methylation levels at low coverage sites using a CNN model in WGBS
DNA methylation is an important regulator of gene transcription. WGBS is the gold-standard
approach for base-pair resolution quantitative of DNA methylation. It requires high …
approach for base-pair resolution quantitative of DNA methylation. It requires high …
ASHFormer: axial and sliding window based attention with high-resolution transformer for automatic stratigraphic correlation
N Liu, Z Li, R Liu, H Zhang, J Gao… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
The stratigraphic correlation of well logs is crucial for characterizing subsurface reservoirs.
However, due to the complexity of well logs and the huge amount of well data, manual …
However, due to the complexity of well logs and the huge amount of well data, manual …
Computational methods for single-cell DNA methylome analysis
W Iqbal, W Zhou - Genomics, Proteomics & Bioinformatics, 2023 - academic.oup.com
Dissecting intercellular epigenetic differences is key to understanding tissue heterogeneity.
Recent advances in single-cell DNA methylome profiling have presented opportunities to …
Recent advances in single-cell DNA methylome profiling have presented opportunities to …
GraphCpG: imputation of single-cell methylomes based on locus-aware neighboring subgraphs
Motivation Single-cell DNA methylation sequencing can assay DNA methylation at single-
cell resolution. However, incomplete coverage compromises related downstream analyses …
cell resolution. However, incomplete coverage compromises related downstream analyses …
Research progress and application of single-cell sequencing in head and neck malignant tumors
S Qu, M Gong, Y Deng, Y Xiang, D Ye - Cancer Gene Therapy, 2024 - nature.com
Single-cell sequencing (SCS) is a technology that separates thousands of cells from the
organism and accurately analyzes the genetic material expressed in each cell using high …
organism and accurately analyzes the genetic material expressed in each cell using high …