The presented review is an attempt to summarize a huge volume of data on 5-ene-4-
thiazolidinones being a widely studied class of small molecules used in modern organic and …

Introduction: Rhodanines, as one of the 4-thiazolidinones subtypes, are recognized as
privileged heterocycles in medicinal chemistry. The main achievements include the …

Direct‐acting antiviral agents (DAAs) represent a class of drugs targeting viral proteins and
have been demonstrated to be very successful in combating viral infections in clinic …

In eukaryotic organisms, the orthologs of the DEAD-box RNA helicase Ded1p from yeast
and DDX3 from human form a well-defined subfamily that is characterized by high sequence …

Since the discovery of the DNA double helix, there has been a fascination in understanding
the molecular mechanisms and cellular processes that account for:(i) the transmission of …

Traditional functions of DExD/H-box helicases are concerned with RNA metabolism; they
have been shown to play a part in nearly every cellular process that involves RNA. On the …

The DEAD-box RNA helicase DDX3 is a multifunctional protein involved in all aspects of
RNA metabolism, including transcription, splicing, mRNA nuclear export, translation, RNA …

Targeting a host factor essential for the replication of different viruses but not for the cells
offers a higher genetic barrier to the development of resistance, may simplify therapy …

The human DEAD-box RNA helicase DDX3 has been implicated to play a role in the whole
repertoire of processes regulating gene expression, including transcription, splicing, mRNA …

Cancer is one of the most studied areas of human biology over the past century. Despite
having attracted much attention, hype, and investments, the search to find a cure for cancer …