The 18 glycosyl hydrolase family of chitinases is an ancient gene family that is widely
expressed from prokaryotes to eukaryotes. In mammals, despite the absence of endogenous …

Chitooligosaccharides (CHOS) are homo-or heterooligomers of N-acetylglucosamine and D-
glucosamine. CHOS can be produced using chitin or chitosan as a starting material, using …

Chitin is a surface component of parasites and insects, and chitinases are induced in lower
life forms during infections with these agents. Although chitin itself does not exist in humans …

Plasmodium sporozoites are the product of a complex developmental process in the
mosquito vector and are destined to infect the mammalian liver. Attention has been drawn to …

The mosquito midgut stages of malaria parasites are crucial for establishing an infection in
the insect vector and to thus ensure further spread of the pathogen. Parasite development in …

Nearly one million people are killed every year by the malaria parasite Plasmodium.
Although the disease-causing forms of the parasite exist only in the human blood …

Recent findings concerning Drosophila melanogaster intestinal pathology suggest that this
model is well suited for the study of intestinal stem cell physiology during aging, stress and …

A family of apicomplexa-specific proteins containing AP2 DNA-binding domains (ApiAP2s)
was identified in malaria parasites. This family includes sequence-specific transcription …

Manipulation of the mosquito gut microbiota can lay the foundations for novel methods for
disease transmission control. Mosquito blood feeding triggers a significant, transient …

The sexual phase of the malaria pathogen, Plasmodium falciparum, culminates in
fertilization within the midgut of the mosquito and represents a crucial step in the completion …