In their 60-year history, dapsone and the sulfones have been used as both antibacterial and
anti-inflammatory agents. Dapsone has been used successfully to treat a range of …

Idiosyncratic drug reactions are unpredictable reactions that can result in significant
morbidity and mortality. Severe idiosyncratic drug reactions are often characterised by fever …

Because of the increasing use of immunosuppressive and biological drugs, the occurrence
of opportunistic infections has become a key safety issue for patients with inflammatory …

Introduction: In their 70-year history, dapsone and other sulfones have been used as both
antibacterial and anti-inflammatory agents. Dapsone has been the main active principle in …

Classical and nonclassical isosteric C8− N9 bridged analogues of the multitargeted
antifolate LY231514 were synthesized as inhibitors of thymidylate synthase (TS) …

Pneumocystis jirovecii pneumonia (PJP) is an opportunistic infection that mostly affects
children with suppressed cellular immunity. PJP was the most common cause of infectious …

Opportunistic infections are known to cause morbidity and mortality in immunocompromised
individuals. In addition, serious infections due to several parasites are also known to affect …

Exosome fractions of dendritic cells (DC) produced in long-term cultures (LTC) were found to
contain Mycoplasma contaminants. In this study, Mycoplasma-infected,-uninfected, and …

Background Clindamycin is an antibiotic used in anaerobic and severe complicated
infections. It is often selected for patients with a history of allergy to other antibiotics …

Four diphenylfuran derivatives possessing different dicationic terminal side chains were
used to investigate sequence-specific binding to DNA and poisoning of human …