New genetic and epigenetic insights into the chemokine system: the latest discoveries aiding progression toward precision medicine

H Xu, S Lin, Z Zhou, D Li, X Zhang, M Yu… - Cellular & Molecular …, 2023 - nature.com
Over the past thirty years, the importance of chemokines and their seven-transmembrane G
protein-coupled receptors (GPCRs) has been increasingly recognized. Chemokine …

Spotlight on contributory role of host immunogenetic profiling in SARS-CoV-2 infection: Susceptibility, severity, mortality, and vaccine effectiveness

S Yazdanparast, M Bakhtiyaridovvombaygi, F Mikanik… - Life Sciences, 2023 - Elsevier
Abstract Background The SARS-CoV-2 virus has spread continuously worldwide,
characterized by various clinical symptoms. The immune system responds to SARS-CoV-2 …

[HTML][HTML] Adverse effect of VEGFR-2 (rs1870377) polymorphism on the clinical course of COVID-19 in females and males in an age-dependent manner

DBS Kocakap, S Kaygusuz, E Aksoy, Ö Şahin… - Microbes and …, 2023 - Elsevier
The COVID-19 pandemic has affected people worldwide with varying clinical presentations
ranging from mild to severe or fatal, and studies have found that age, gender, and some …

Genetic Variants and Protective Immunity against SARS-CoV-2

AA Rabaan, AA Mutair, M Aljeldah, BRA Shammari… - Genes, 2022 - mdpi.com
The novel coronavirus-19 (SARS-CoV-2), has infected numerous individuals worldwide,
resulting in millions of fatalities. The pandemic spread with high mortality rates in multiple …

Role of the Neanderthal Genome in Genetic Susceptibility to COVID-19: 3p21. 31 Locus in the Spotlight

M Yaghmouri, P Izadi - Biochemical Genetics, 2024 - Springer
Since the outbreak of COVID-19, genome-wide association studies have tried to discover
the role of genetic predisposition in the clinical variability of this viral infection. The findings …

CXCL12/CXCR4 as a potential axis in diagnosis and predicting disease severity in COVID-19 patients: a new perspective

AL Ozkaya, E Laloğlu, AH Gul, N Çelik - Turkish Journal of …, 2024 - degruyter.com
Abstract Objectives Coronavirus disease 2019 (COVID-19) exhibits variations in terms of
patients' clinical symptoms and levels of routinely employed biochemical markers. The aim …

Screening Herbal Compound Candidates for Use as Anti-Inflammatory Drugs for COVID-19 Treatment Using Deep Semisupervised Learning

IA Khalid, WAK Kusuma, K Priandana… - Indonesian Journal of …, 2023 - journal.ugm.ac.id
COVID-19 is a disease caused by the SARS-CoV-2 virus. Its symptoms include cough, fever,
shortness of breath, and acute inflammation (hyperinflammation), and severe cases can …

Effect of MCP-1 and CCR2 Serum Levels on COVID-19 Severity

SZM Kömürcü, Ş Doğan, E Kaya, S Yavaş, S Doğan… - Experimed, 2023 - dergipark.org.tr
Objective: Approximately 80% of people with coronavirus disease 2019 (COVID-19) are
asymptomatic, and only a small proportion of cases show serious consequences leading to …

Effect of MCP-1 and CCR2 Serum Levels on COVID-19 Severity.

SZ Mart Komurcu, S Dogan, E Kaya, S Yavas… - …, 2023 - search.ebscohost.com
Objective: Approximately 80% of people with Coronavirus disease 2019 (COVID-19) are
asymptomatic, and only a small proportion of cases show serious consequences leading to …