Diabetes is a systemic disease in which patients with diabetes may develop peripheral
neuropathy of the lower extremities and peripheral vascular disease due to long-term …

Background Non-alcoholic fatty liver disease (NAFLD) is a spectrum of disease ranging from
simple hepatic steatosis (NAFL) to non-alcoholic steatohepatitis (NASH) which may …

Neurodegenerative diseases (NDs) are currently incurable diseases that cause progressive
degeneration of nerve cells. Many of the disease-causing proteins of NDs are “undruggable” …

During the onset of liver fibrosis, capillarized liver sinusoidal endothelial cells (LSECs) limit
substance exchange between the blood and the Disse space, further accelerating hepatic …

Nonalcoholic fatty liver disease (NAFLD) affects approximately 25% of the adult population
worldwide. This pathology can progress into end-stage liver disease with life-threatening …

Cell survival rate determines engraftment efficiency in adipose-derived mesenchymal stem
cell (ADSC)-based regenerative medicine. In vivo monitoring of ADSC viability to achieve …

Chronic liver diseases from varying etiologies generally lead to liver fibrosis and cirrhosis.
Among them, non-alcoholic fatty liver disease (NAFLD) affects roughly one-quarter of the …

Diabetes is a chronic metabolic disease, and its therapeutic goals focus on the effective
management of blood glucose and various complications. Drug combination therapy has …

Oral administration is the preferred route of administration based on the convenience for and
compliance of the patient. Oral nanomedicines have been developed to overcome the …

Metabolic diseases, including obesity, diabetes, and nonalcoholic fatty liver disease
(NAFLD), are rising in both incidence and prevalence and remain a major global health and …