An emerging literature from epidemiologic, clinical, and preclinical investigations has
provided evidence that gestational exposure to infection contributes to the etiology of …

Improvements in health care have greatly increased life span in the United States. The focus
is now shifting from physical well-being to improvement in mental well-being or maintenance …

Recent studies have established the involvement of the fat mass and obesity-associated
gene (FTO) in metabolic disorders such as obesity and diabetes. However, the precise …

We have used a translational convergent functional genomics (CFG) approach to identify
and prioritize genes involved in schizophrenia, by gene-level integration of genome-wide …

Recent studies are beginning to paint a clear and consistent picture of the impairments in
psychological and cognitive competencies that are associated with microdeletions in …

Although our knowledge of the pathophysiology of schizophrenia has increased, treatments
for this devastating illness remain inadequate. Here, we critically assess rodent models and …

Abstract Background 22q11. 2 deletion syndrome (22q11DS), a copy number variation
(CNV) disorder, occurs in approximately 1: 4000 live births due to a heterozygous …

Over the last fifteen years it has become established that 22q11. 2 deletion syndrome
(22q11DS) is a true genetic risk factor for schizophrenia. Carriers of deletions in …

Effects of an 18-month treatment with a moderate, chronic caloric restriction (CR) or an oral
supplementation with resveratrol (RSV), a potential CR mimetic, on cognitive and motor …

Patients with schizophrenia are at an increased risk for the development of depression.
Overlap in the symptoms and genetic risk factors between the two disorders suggests a …