Simple Summary Patients with glioblastoma—the most frequent and malignant primary brain
tumor—have a poor prognosis with a median survival of less than 15 months. Despite …

Glioma represents a fast proliferating and highly invasive brain tumor which is resistant to
current therapies and invariably recurs. Despite some advancements in anti-glioma …

Recent studies have shown the importance of the dynamic tumor microenvironment (TME) in
high-grade gliomas (HGGs). In particular, myeloid cells are known to mediate …

Glioblastoma (GBM) is a common and highly malignant primary tumor of the central nervous
system in adults. Ever more recent papers are focusing on understanding the role of the …

The application of tumor immunotherapy to glioblastoma (GBM) is limited by an
unprecedented degree of immune suppression due to factors that include high numbers of …

Simple Summary The aim of this review is to summarize the available information regarding
the MIF family in cancer, comprising MIF and DDT. Both cytokines are highly expressed in …

Progressive brain diseases create a huge social and economic burden on modern societies
as a major cause of disability and death. Incidence of brain diseases has a significantly …

Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine that serves many
roles in inflammation and immunity; however, it is also involved in carcinogenesis. This is a …

Simple Summary Glioblastoma is a devastating malignancy that has continued to prove
resistant to a variety of therapeutics. No new systemic therapy has been approved for use …

Glioblastoma (GBM) is the most common primary malignant brain tumor in adults with an
extremely poor prognosis. There is a dire need to develop effective therapeutics to …