The non‐neuronal and nonmuscular effects of botulinum toxin: an opportunity for a deadly molecule to treat disease in the skin and beyond

SA Grando, CB Zachary - British Journal of Dermatology, 2018 - academic.oup.com
There is growing evidence that botulinum neurotoxins (BoNTs) exhibit biological effects on
various human cell types with a host of associated clinical implications. This review aims to …

The use of botulinum toxin in flap surgery: a review of the literature

F Segreto, GF Marangi, M Signoretti… - Surgical …, 2019 - journals.sagepub.com
Botulinum neurotoxin-A and botulinum neurotoxin-B have been shown to play a potential
role in improving flap survival in animal models. The aim of this study is to review indications …

[HTML][HTML] Intramuscular neural arborization of the latissimus dorsi muscle: application of botulinum neurotoxin injection in flap reconstruction

KH Yi, HJ Lee, KK Seo, HJ Kim - Toxins, 2022 - mdpi.com
Postoperative pain after breast reconstruction surgery with the latissimus dorsi flap is a
common occurrence. Botulinum neurotoxin (BoNT) injection during surgery is effective in …

Visualizing the pharmacologic preconditioning effect of botulinum toxin type A by infrared thermography in a rat pedicled perforator island flap model

M Chen, X Li, Z Jiang, X Gong - Plastic and reconstructive surgery, 2019 - journals.lww.com
Background: Surgical delay can improve flap viability, leading to vasodilation,
neovascularization, and vessel reorganization. Experiments suggest a similar positive effect …

[HTML][HTML] Application of botulinum neurotoxin injections in TRAM flap for breast reconstruction: intramuscular neural arborization of the rectus abdominis muscle

KH Yi, HJ Lee, JH Lee, KK Seo, HJ Kim - Toxins, 2021 - mdpi.com
Breast reconstruction after mastectomy is commonly performed using transverse rectus
abdominis myocutaneous (TRAM) flap. Previous studies have demonstrated that botulinum …

Botulinum neurotoxin injection guidelines regarding flap surgeries in breast reconstruction

KH Yi, HJ Lee, KK Seo, HJ Kim - Journal of Plastic, Reconstructive & …, 2022 - jprasurg.com
Breast cancer is one of the most diagnosed cancers, accounting for over 30% of all cancers
in women. The incidence of breast cancer continues to increase annually, but mortality has …

The effects of botulinum toxin A on pain in ischemic vasospasm

SH Goldberg, A Akoon, HL Kirchner… - The Journal of Hand …, 2021 - Elsevier
Purpose The purpose was to describe the impact of botulinum toxin A (BTX-A)
administration in patients with ischemic vasospasm on the magnitude and timing of pain …

[HTML][HTML] The Effect of Botulinum Toxin A on the NADPH Oxidase System and Ischemia-Reperfusion Injury

HW Kyung, S Lee, H Kwon, S Kim, JH Kim… - Plastic and …, 2024 - journals.lww.com
Background: Despite the increasing popularity of various materials for ischemia-reperfusion
(I/R) injury mitigation, research on botulinum toxin type A (BoNTA) remains limited. This …

Effects of açaí and cilostazol on skin microcirculation and viability of TRAM flaps in hamsters

DSC da Mota, FL Sicuro, AC Resende… - Journal of Surgical …, 2018 - Elsevier
Background Tissue necrosis caused by insufficient perfusion is a major complication in flap
transfer. This study evaluated whether treatment with cilostazol or hydroalcoholic extract of …

Effects of botulinum toxin A on the blood flow in expanded rat skin

H Liu, Z Yu, J Wang, X Zhang, L Lei… - Journal of …, 2022 - Taylor & Francis
Background Poor blood supply can easily lead to expander extrusion and necrosis at the
distal expanded flap. Botulinum toxin A (BTX-A) has been previously found to improve …