[HTML][HTML] Principles and applications of liquid chromatography-mass spectrometry in clinical biochemistry

JJ Pitt - The Clinical Biochemist Reviews, 2009 - ncbi.nlm.nih.gov
Liquid chromatography-mass spectrometry (LC-MS) is now a routine technique with the
development of electrospray ionisation (ESI) providing a simple and robust interface. It can …

Chemical derivatization and mass spectral libraries in metabolic profiling by GC/MS and LC/MS/MS

JM Halket, D Waterman… - Journal of …, 2005 - academic.oup.com
An overview is presented of gas chromatography/mass spectrometry (GC/MS) and liquid
chromatography/mass spectrometry (LC/MS), the two major hyphenated techniques …

High rates of non-adherence to antihypertensive treatment revealed by high-performance liquid chromatography-tandem mass spectrometry (HP LC-MS/MS) urine …

M Tomaszewski, C White, P Patel, N Masca, R Damani… - Heart, 2014 - heart.bmj.com
Objectives Non-adherence to therapy is an important cause of suboptimal blood pressure
control but few practical tools exist to accurately and routinely detect it. We used a simple …

Increased BDNF promoter methylation in the Wernicke area of suicide subjects

S Keller, M Sarchiapone, F Zarrilli… - Archives of general …, 2010 - jamanetwork.com
Context Brain-derived neurotrophic factor (BDNF) plays a pivotal role in the pathophysiology
of suicidal behavior andBDNFlevels are decreased in the brain and plasma of suicide …

New challenges and innovation in forensic toxicology: focus on the “New Psychoactive Substances”

D Favretto, JP Pascali, F Tagliaro - Journal of chromatography A, 2013 - Elsevier
In the recent years, new molecules have appeared in the illicit market, claimed to contain
“non-illegal” compounds, although exhibiting important psychoactive effects; this …

Development of a multi‐target screening analysis for 301 drugs using a QTrap liquid chromatography/tandem mass spectrometry system and automated library …

CA Mueller, W Weinmann, S Dresen… - … Journal Devoted to …, 2005 - Wiley Online Library
A new multi‐target screening (MTS) procedure for drugs in blood and urine for toxicological
analysis has been developed using a hybrid triple‐quadrupole linear ion trap mass …

Detection and identification of 700 drugs by multi-target screening with a 3200 Q TRAP® LC-MS/MS system and library searching

S Dresen, N Ferreirós, H Gnann… - Analytical and …, 2010 - Springer
The multi-target screening method described in this work allows the simultaneous detection
and identification of 700 drugs and metabolites in biological fluids using a hybrid triple …

Applying 'Sequential Windowed Acquisition of All Theoretical Fragment Ion Mass Spectra'(SWATH) for systematic toxicological analysis with liquid chromatography …

K Arnhard, A Gottschall, F Pitterl… - Analytical and bioanalytical …, 2015 - Springer
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become an
indispensable analytical technique in clinical and forensic toxicology for detection and …

Simultaneous screening for 238 drugs in blood by liquid chromatography–ionspray tandem mass spectrometry with multiple-reaction monitoring

M Gergov, I Ojanperä, E Vuori - Journal of Chromatography B, 2003 - Elsevier
A liquid chromatography–tandem mass spectrometry (LC–MS–MS) method is presented for
the qualitative screening for 238 drugs in blood samples, which is considerably more than in …

How to screen for non-adherence to antihypertensive therapy

P Gupta, P Patel, R Horne, H Buchanan… - Current hypertension …, 2016 - Springer
The quality of assessment of non-adherence to treatment in hypertensive is poor. Within this
review, we discuss the different methods used to assess adherence to blood-pressure …