Lipid-based nanoparticles for delivery of vaccine adjuvants and antigens: toward multicomponent vaccines
D Chatzikleanthous, DT O'Hagan… - Molecular …, 2021 - ACS Publications
Despite the many advances that have occurred in the field of vaccine adjuvants, there are
still unmet needs that may enable the development of vaccines suitable for more …
still unmet needs that may enable the development of vaccines suitable for more …
Liposomes used as a vaccine adjuvant-delivery system: From basics to clinical immunization
N Wang, M Chen, T Wang - Journal of Controlled Release, 2019 - Elsevier
Liposomes are widely utilized as a carrier to improve therapeutic efficacy of agents thanks to
their merits of high loading capacity, targeting delivery, reliable protection of agents, good …
their merits of high loading capacity, targeting delivery, reliable protection of agents, good …
Liposome and immune system interplay: Challenges and potentials
Liposome as a revolutionizing carrier, has exhibited favorable aspects in drug delivery.
However, there are numerous challenges affecting its effectiveness. Hypersensitivity …
However, there are numerous challenges affecting its effectiveness. Hypersensitivity …
Recent advances in intranasal liposomes for drug, gene, and vaccine delivery
Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles
produced from cholesterol and phospholipids. Recently, liposomes have been widely …
produced from cholesterol and phospholipids. Recently, liposomes have been widely …
Vaccine approaches for antigen capture by liposomes
Introduction Liposomes have been used as carriers for vaccine adjuvants and antigens due
to their inherent biocompatibility and versatility as delivery vehicles. Two vial admixture of …
to their inherent biocompatibility and versatility as delivery vehicles. Two vial admixture of …
The role of mucoadhesion and mucopenetration in the immune response induced by polymer-based mucosal adjuvants
Mucus is a viscoelastic gel that acts as a protective barrier for epithelial surfaces. The
mucosal vehicles and adjuvants need to pass through the mucus layer to make drugs and …
mucosal vehicles and adjuvants need to pass through the mucus layer to make drugs and …
Long-term generation of antiPCSK9 antibody using a nanoliposome-based vaccine delivery system
Background and aims Proprotein convertase subtilisin kexin type 9 (PCSK9) is a liver
secretory enzyme that controls plasma low-density lipoprotein cholesterol (LDL-C) levels …
secretory enzyme that controls plasma low-density lipoprotein cholesterol (LDL-C) levels …
Developing oral nanovaccines for fish: A modern trend to fight infectious diseases
C Angulo, M Tello‐Olea, M Reyes‐Becerril… - Reviews in …, 2021 - Wiley Online Library
Nanovaccines constitute an innovative approach in vaccinology, enabled by the
nanotechnology advances on the synthesis, functionalization and application of …
nanotechnology advances on the synthesis, functionalization and application of …
Development of COVID-19 vaccine using a dual Toll-like receptor ligand liposome adjuvant
We developed a SARS-CoV-2 spike subunit vaccine formulation containing dual TLR ligand
liposome adjuvant. The vaccine-induced robust systemic neutralizing antibodies and …
liposome adjuvant. The vaccine-induced robust systemic neutralizing antibodies and …
Co-encapsulation of synthetic lipidated TLR4 and TLR7/8 agonists in the liposomal bilayer results in a rapid, synergistic enhancement of vaccine-mediated humoral …
KK Short, SM Miller, L Walsh, V Cybulski… - Journal of Controlled …, 2019 - Elsevier
To increase vaccine immunogenicity, modern vaccines incorporate adjuvants, which serve
to enhance immune cross-protection, improve humoral and cell-mediated immunity, and …
to enhance immune cross-protection, improve humoral and cell-mediated immunity, and …