All neuronal circuits are subject to neuromodulation. Modulatory effects on neuronal
processing and resulting behavioral changes are most commonly reported for higher order …

The thalamus is a key structure that controls the routing of information in the brain.
Understanding modulation at the thalamic level is critical to understanding the flow of …

Visual hallucinations (VH) are commonly found in the course of synucleinopathies like
Parkinson's disease and dementia with Lewy bodies. The incidence of VH in these …

The thalamus (comprising many distinct nuclei) plays a key role in facilitating sensory
discrimination and cognitive processes through connections with the cortex. Impaired …

Most neurological diseases have a multifactorial nature and the number of molecular
mechanisms discovered as underpinning these diseases is continuously evolving. The old …

Cognitive deficits in individuals with schizophrenia (SCZ) are considered core symptoms of
this disorder, and can manifest at the prodromal stage. Antipsychotics ameliorate positive …

It is generally thought that neurons in the thalamic reticular nucleus (TRN) form GABAergic
synapses with other TRN neurons and that these interconnections are important for the …

Alterations in the function of the medial prefrontal cortex (mPFC) and its major thalamic
source of innervation, the mediodorsal (MD) thalamus, have been hypothesized to …

One of the core diagnostic criteria for Dementia with Lewy Bodies (DLB) is the presence of
visual hallucinations. The presence of hallucinations, along with fluctuations in the level of …

Dynamic binding of different brain areas is critical for various cognitive functions. The
thalamic reticular nucleus (TRN) is a GABAergic nucleus that constrains information flow …